Coro1A antibody | OTI1A5
Mouse anti Human CORO1A antibody, clone OTI1A5 recognizes coronin-1A, also known as clipin-A, coronin-1, coronin-1A, coronin-like protein A, coronin-like protein p57 and tryptophan aspartate-containing coat protein.
Encoded by the CORO1A gene, coronin-1A is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16 (provided by RefSeq, Sep 2010).
Mouse anti Human CORO1A antibody, clone OTI1A5 detects a band of 51 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Encoded by the CORO1A gene, coronin-1A is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16 (provided by RefSeq, Sep 2010).
Mouse anti Human CORO1A antibody, clone OTI1A5 detects a band of 51 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti CORO1A detects a band of approximately 51 kDa in Jurkat cell lysates
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Mouse monoclonal antibody purified by affinity chromatography from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
50% Glycerol - Immunogen
- Full length ecombinant human CORO1A (NP_009005) produced in HEK293T cells
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P31146
- Entrez Gene
- CORO1A
- GO Terms
- GO:0001845 phagolysosome assembly
- GO:0001891 phagocytic cup
- GO:0051015 actin filament binding
- GO:0008022 protein C-terminus binding
- GO:0030027 lamellipodium
- GO:0030670 phagocytic vesicle membrane
- GO:0030864 cortical actin cytoskeleton
- GO:0031589 cell-substrate adhesion
- GO:0031941 filamentous actin
- GO:0042803 protein homodimerization activity
- GO:0043548 phosphatidylinositol 3-kinase binding
- GO:0045087 innate immune response
- GO:0050918 positive chemotaxis
- GO:0051126 negative regulation of actin nucleation
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of Coro1A antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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