COMMD1 antibody | OTI3B3
Mouse anti COMMD1
COMMD1 antibody recognizes the COMM domain-containing protein 1, also known as MURR1. The antibody has been extensively validated for western blotting using whole cell lysates.
- Product Type
- PrecisionAb™ Monoclonal
- Clone
- OTI3B3
- Isotype
- IgG1
- Format
- Purified
| Product Code | Applications | Datasheet | MSDS | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|---|
| VMA00146 | WB | 100 µl |
Mouse anti Human COMMD1 antibody recognizes COMMD1, also known as COMM domain-containing protein 1, copper metabolism gene MURR1 and protein Murr1. COMMD1 is a regulator of copper homeostasis, sodium uptake, and NF-kappa-B signaling (de Bie et al. 2005).
Mouse anti Human COMMD1 antibody detects a band of 21 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Mouse anti Human COMMD1 antibody detects a band of 21 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti COMMD1 detects a band of approximately 21 kDa in K562 cell lysates.
- Product Form
- Purified IgG - liquid
- Preparation
- Mouse monoclonal antibody purified by affinity chromatography from ascites.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
50% Glycerol - Immunogen
- Full length recombinant human COMMD1 (NP_689729) produced in HEK293T cells
- Instructions For Use
- Please refer to the PrecisionAb western blotting protocol. For additional information on secondary antibody dilution and exposure time see product web page.
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- As supplied, 12 months from date of despatch.
More Information
- UniProt
- Q8N668 Related reagents
- Entrez Gene
- COMMD1 Related reagents
- GO Terms
- GO:0005507 copper ion binding
- GO:0005737 cytoplasm
- GO:0005730 nucleolus
- GO:0030054 cell junction
- GO:0031398 positive regulation of protein ubiquitination
- GO:0031462 Cul2-RING ubiquitin ligase complex
- GO:0032088 negative regulation of NF-kappaB transcription factor activity
- GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process
- GO:0042803 protein homodimerization activity
- GO:0055070 copper ion homeostasis
- Acknowledgements
- PrecisionAb™ is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of COMMD1 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
PrecisionAb antibodies have been extensively validated for the western blot application. The antibody has been validated at the suggested dilution. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.
Copyright © 2019 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
| Description | Product Code | Pack Size | Applications | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | 2 ml | WB |
Product Specific References
Further Reading
-
de Bie P et al. (2005) The many faces of the copper metabolism protein MURR1/COMMD1.
J Hered. 96 (7): 803-11.
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