CLIC1 antibody | CPTC32

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Mouse anti CLIC1

Product Type
PrecisionAb Monoclonal
Clone
CPTC32
Isotype
IgG2a
Format
Purified
Product Code Applications Pack Size List Price Quantity
VMA00555
Datasheet
WB
MSDS
100 µl loader

Mouse anti Human CLIC1 antibody recognizes the chloride intracellular channel 1, also known as RNCC protein, chloride channel ABP or nuclear chloride ion channel 27.

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity (provided by RefSeq, Jul 2008).

Mouse anti Human CLIC1 antibody detects a band of 27 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti CLIC1 detects a band of approximately 27 kDa in K562 cell lysates
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Recombinant protein of human CLIC1

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Guarantee
As supplied, 12 months from date of despatch.

More Information

UniProt
O00299 Related reagents
Entrez Gene
CLIC1 Related reagents
GO Terms
GO:0005886 plasma membrane
GO:0005515 protein binding
GO:0007165 signal transduction
GO:0005247 voltage-gated chloride channel activity
GO:0005624 membrane fraction
GO:0005625 soluble fraction
GO:0005737 cytoplasm
GO:0005903 brush border
GO:0031965 nuclear membrane
GO:0034707 chloride channel complex
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of CLIC1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml

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