Cdc2 is a highly conserved protein with an important role in cell cycle progression and DNA break repair. Cdc2 overexpression in malignant tumor cells may play a role in tumor progression and be indicative of prognostic. Mouse anti Human Cdc2 antibody detects a band of 34 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
- Target Species
- Western Blotting
- Anti Cdc2 detects a band of approximately 34 kDa in Jurkat cell lysates.
- Product Form
- Purified IgG - liquid
- Mouse monoclonal antibody purified by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Recombinant human p34 cdc2 fusion protein
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- As supplied, 12 months from date of despatch.
- P06493 Related reagents
- Entrez Gene
- CDK1 Related reagents
- GO Terms
- GO:0000083 regulation of transcription involved in G1/S phase of mitotic cell cycle
- GO:0000186 activation of MAPKK activity
- GO:0000187 activation of MAPK activity
- GO:0002755 MyD88-dependent toll-like receptor signaling pathway
- GO:0002756 MyD88-independent toll-like receptor signaling pathway
- GO:0005829 cytosol
- GO:0004693 cyclin-dependent protein kinase activity
- GO:0005524 ATP binding
- GO:0005654 nucleoplasm
- GO:0005876 spindle microtubule
- GO:0006916 anti-apoptosis
- GO:0007067 mitosis
- GO:0007173 epidermal growth factor receptor signaling pathway
- GO:0007265 Ras protein signal transduction
- GO:0007411 axon guidance
- GO:0008063 Toll signaling pathway
- GO:0008286 insulin receptor signaling pathway
- GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity
- GO:0030496 midbody
- GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
- GO:0034130 toll-like receptor 1 signaling pathway
- GO:0034134 toll-like receptor 2 signaling pathway
- GO:0034138 toll-like receptor 3 signaling pathway
- GO:0034142 toll-like receptor 4 signaling pathway
- GO:0034501 protein localization to kinetochore
- GO:0045087 innate immune response
- GO:0048011 nerve growth factor receptor signaling pathway
- GO:0051301 cell division
- GO:0051403 stress-activated MAPK cascade
- GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- For research purposes only
Applications of Cdc2 antibody
|Application Name||Verified||Min Dilution||Max Dilution|
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.
Secondary Antibodies Available
|Description||Product Code||Applications||Pack Size||List Price||Quantity|
|Goat anti Mouse IgG (H/L):HRP||STAR207P||WB||2 ml|
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