CD80 antibody | OTI2B11

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Mouse anti CD80

Product Type
PrecisionAb Monoclonal
Product Code Applications Pack Size List Price Quantity
100 µl loader

Mouse anti Human CD80 antibody recognizes CD80, also known as B-lymphocyte activation antigen B7, CD80 antigen (CD28 antigen ligand 1, B7-1 antigen), CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD80, activation B7-1 antigen, costimulatory factor CD80 and costimulatory molecule variant IgV-CD80.

CD80 is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy (provided by RefSeq, Aug 2011).

Mouse anti Human CD80 antibody detects a band of 60 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Western Blotting
Anti CD80 detects a band of approximately 60 kDa in Raji cell lysates.
Product Form
Purified IgG - liquid
Mouse monoclonal antibody purified by affinity chromatography from ascites.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
50% Glycerol
Full length recombinant human CD80 (NP_005182) produced in HEK293T cells

Storage Information

Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
12 months from date of despatch

More Information

Entrez Gene
GO Terms
GO:0005515 protein binding
GO:0016021 integral to membrane
GO:0035556 intracellular signal transduction
GO:0007267 cell-cell signaling
GO:0009967 positive regulation of signal transduction
GO:0015026 coreceptor activity
GO:0016563 transcription activator activity
GO:0031295 T cell costimulation
GO:0042110 T cell activation
GO:0044419 interspecies interaction between organisms
GO:0045086 positive regulation of interleukin-2 biosynthetic process
GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process
GO:0045627 positive regulation of T-helper 1 cell differentiation
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
PrecisionAb is a trademark of Bio-Rad Laboratories.
For research purposes only

Applications of CD80 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml

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