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CD56 antibody | ERIC-1

Product Code Applications Pack Size List Price Your Price Qty
MCA591T
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SDS Safety Datasheet SDS
C E IB 25 µg loader
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loader
MCA591
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
C E IB 0.2 mg loader
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loader

Mouse anti Human CD56 antibody, clone ERIC-1 recognizes N-CAM expressed on developing and adult neuroectodermal tissues in humans. Neuroectodermal tumours also stain including Glioma, ependymoma, neuroblastoma, medulloblastoma, retinoblastoma and teratoma. Oat cell carcinoma and Wilms tumour are also highly reactive. Mouse anti Human CD56 antibody, clone ERIC-1 will react on Natural Killer cells and recognizes 140, 180 and 120 kDa NCAM isoforms.

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
<0.1% Sodium Azide (NaN3)
Immunogen
Human retinoblastoma tumour cells.
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Fusion Partners
Spleen cells from immunized BALB/c mice were fused with cells of the P3/X63.Ag8 mouse myeloma line.
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 80ng/ml
Flow Cytometry
Immunoblotting
Immunohistology - Frozen 1/50 1/100
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
Histology Positive Control Tissue
Neuroblastoma

Description Product Code Applications Pack Size List Price Your Price Quantity
Goat anti Mouse IgG (H/L):Alk. Phos. (Multi Species Adsorbed) STAR117A E WB 0.5 mg loader
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Description Goat anti Mouse IgG (H/L):Alk. Phos. (Multi Species Adsorbed)
Goat anti Mouse IgG (H/L):DyLight®488 (Multi Species Adsorbed) STAR117D488GA F IF 0.1 mg loader
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Description Goat anti Mouse IgG (H/L):DyLight®488 (Multi Species Adsorbed)
Goat anti Mouse IgG (H/L):DyLight®550 (Multi Species Adsorbed) STAR117D550 F IF WB 0.1 mg loader
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Description Goat anti Mouse IgG (H/L):DyLight®550 (Multi Species Adsorbed)
Goat anti Mouse IgG (H/L):DyLight®650 (Multi Species Adsorbed) STAR117D650 F IF 0.1 mg loader
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Description Goat anti Mouse IgG (H/L):DyLight®650 (Multi Species Adsorbed)
Goat anti Mouse IgG (H/L):DyLight®680 (Multi Species Adsorbed) STAR117D680GA F WB 0.1 mg loader
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Description Goat anti Mouse IgG (H/L):DyLight®680 (Multi Species Adsorbed)
Goat anti Mouse IgG (H/L):DyLight®800 (Multi Species Adsorbed) STAR117D800GA F IF WB 0.1 mg loader
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Description Goat anti Mouse IgG (H/L):DyLight®800 (Multi Species Adsorbed)
Goat anti Mouse IgG (H/L):FITC (Multi Species Adsorbed) STAR117F F 0.5 mg loader
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Description Goat anti Mouse IgG (H/L):FITC (Multi Species Adsorbed)
Goat anti Mouse IgG (H/L):HRP (Multi Species Adsorbed) STAR117P C E WB 0.5 mg loader
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Description Goat anti Mouse IgG (H/L):HRP (Multi Species Adsorbed)
Goat anti Mouse IgG (Fc):FITC STAR120F C F 1 mg loader
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Description Goat anti Mouse IgG (Fc):FITC
Goat anti Mouse IgG (Fc):HRP STAR120P E WB 1 mg loader
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Description Goat anti Mouse IgG (Fc):HRP
Rabbit F(ab')2 anti Mouse IgG:RPE STAR12A F 1 ml loader
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Description Rabbit F(ab')2 anti Mouse IgG:RPE
Rabbit F(ab')2 anti Mouse IgG:HRP (Human Adsorbed) STAR13B C E P RE WB 1 mg loader
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Description Rabbit F(ab')2 anti Mouse IgG:HRP (Human Adsorbed)
Goat anti Mouse IgG:FITC (Rat Adsorbed) STAR70 F 0.5 mg loader
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Description Goat anti Mouse IgG:FITC (Rat Adsorbed)
Goat anti Mouse IgG:RPE (Rat Adsorbed) STAR76 F 1 ml loader
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Description Goat anti Mouse IgG:RPE (Rat Adsorbed)
Goat anti Mouse IgG:HRP (Rat Adsorbed) STAR77 C E P 0.5 mg loader
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Description Goat anti Mouse IgG:HRP (Rat Adsorbed)
Goat anti Mouse IgG/A/M:HRP (Human Adsorbed) STAR87P E 1 mg loader
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Description Goat anti Mouse IgG/A/M:HRP (Human Adsorbed)
Rabbit F(ab')2 anti Mouse IgG:FITC STAR9B F 1 mg loader
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Description Rabbit F(ab')2 anti Mouse IgG:FITC

References for CD56 antibody

  1. Bourne, S.P. et al. (1991) A monoclonal antibody (ERIC-1), raised against retinoblastoma, that recognizes the neural cell adhesion molecule (NCAM) expressed on brain and tumours arising from the neuroectoderm.
    J Neurooncol. 10 (2): 111-9.
  2. Criel, A. et al. (1997) Further characterization of morphologically defined typical and atypical CLL: a clinical, immunophenotypic, cytogenetic and prognostic study on 390 cases.
    Br J Haematol. 97 (2): 383-91.
  3. Cameron, A.L. et al. (2002) Natural killer and natural killer-T cells in psoriasis.
    Arch Dermatol Res. 294 (8): 363-9.
  4. Quenby, S. et al. (2005) Prednisolone reduces preconceptual endometrial natural killer cells in women with recurrent miscarriage.
    Fertil Steril. 84 (4): 980-4.
  5. McIntosh K et al. (2006) The immunogenicity of human adipose-derived cells: temporal changes in vitro.
    Stem Cells. 24 (5): 1246-53.
  6. Whitworth, M.K. et al. (2007) Cervical leukocyte sub-populations in idiopathic preterm labour.
    J Reprod Immunol. 75: 48-55.
  7. Preuße, C. et al. (2012) Immune-mediated necrotizing myopathy is characterized by a specific Th1-M1 polarized immune profile.
    Am J Pathol. 181 (6): 2161-71.
  8. Debeer, S. et al. (2013) Comparative histology and immunohistochemistry of porcine versus human skin.
    Eur J Dermatol. 23 (4): 456-66.
  9. View The Latest Product References
  10. Salvatore, G. et al. (2015) Human monocyte-derived dendritic cells turn into foamy dendritic cells with IL-17A.
    J Lipid Res. 56 (6): 1110-22.
  11. Preuße, C. et al. (2016) Differential roles of hypoxia and innate immunity in juvenile and adult dermatomyositis.
    Acta Neuropathol Commun. 4 (1): 45.
  12. Allenbach, Y. et al. (2016) Dermatomyositis With or Without Anti-Melanoma Differentiation-Associated Gene 5 Antibodies: Common Interferon Signature but Distinct NOS2 Expression.
    Am J Pathol. 186 (3): 691-700.
  13. Siegert, E. et al. (2021) Systemic sclerosis-associated myositis features minimal inflammation and characteristic capillary pathology.
    Acta Neuropathol. 141 (6): 917-27.
  14. Meinhardt, J. et al. (2021) Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19.
    Nat Neurosci. 24 (2): 168-75.
  15. Vogt, S. et al. (2023) Morphological and molecular comparison of HIV-associated and sporadic inclusion body myositis.
    J Neurol. 270 (9): 4434-43.
  16. Englert, B. et al. (2024) "Amyopathic" MDA5-positive dermatomyositis with severe lung involvement presenting with net myositic morphological features- Insights from an autopsy study
    Neuromuscular Disorders. 03 Feb [Epub ahead of print].

Immunohistology - Paraffin

Synonyms
N-CAM
RRID
AB_321501
UniProt
P13591
Entrez Gene
NCAM1

MCA591T

180406

MCA591

155515 160660 163240 170505

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