CD38 antibody | HIT2

Mouse anti Human CD38

Product Type
Monoclonal Antibody
Clone
HIT2
Isotype
IgG1
Specificity
CD38

Product Code Applications Pack Size List Price Your Price Qty
MCA1718GA
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
F 0.1 mg loader
List Price Your Price
loader
Search for Batch Specific Datasheets

Mouse anti Human CD38 antibody, clone HIT2 recognizes human ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, also known as CD38, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase 1 or T10. CD38 is a 300 amino acid ~45 kDa single pass type II transmembrane glycoprotein expressed by activated T cells and by plasma cells.

Target Species
Human
Product Form
Purified IgG - liquid.
Preparation
Purified IgG prepared by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml.
Regulatory
For research purposes only.
Guarantee
Guaranteed for 12 months from the date of despatch or until the date of expiry, whichever comes first. Please see label for expiry date.

Store at +4°C or at -20°C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Flow Cytometry Neat 1/5
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Flow Cytometry
Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood'

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References for CD38 antibody

  1. Summerhill, R.J. et al. (1993) Human lymphocyte antigen CD38 catalyzes the production of cyclic ADP-ribose.
    FEBS Lett. 335 (2): 231-3.

UniProt
P28907
Entrez Gene
CD38
GO Terms
GO:0005886 plasma membrane
GO:0003953 NAD+ nucleosidase activity
GO:0016021 integral to membrane
GO:0004872 receptor activity
GO:0005488 binding
GO:0008624 induction of apoptosis by extracellular signals
GO:0042493 response to drug
GO:0016563 transcription activator activity
GO:0016564 transcription repressor activity
GO:0030890 positive regulation of B cell proliferation
GO:0043066 negative regulation of apoptosis
GO:0050853 B cell receptor signaling pathway
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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