CD338 antibody | BXP-21

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Mouse anti Human CD338

Product Type
Monoclonal Antibody
Clone
BXP-21
Isotype
IgG2a
Product Code Applications Pack Size List Price Quantity
OBT1177
Datasheet
C WB
MSDS
1 ml loader

Mouse anti Human CD338, clone BXP-21 recognises an internal epitope of CD338, otherwise known as the Breast Cancer Resistance Protein (BCRP), a ~70 kDa transmembrane half transporter involved in multidrug resistance. Mouse anti Human CD338, clone BXP-21 does not cross react with human MDR1, MRP1 or MRP2 gene products.

Product Details

Target Species
Human
Product Form
Serum free tissue culture supernatant - liquid
Preservative Stabilisers
0.02%Sodium Azide (NaN3)
0.1%Bovine Serum Albumin
Immunogen
Fusion protein consisting of the E.coli maltose binding protein and a 126 amino acid part of the CD338 peptide corresponding to aa 271-396 of BCRP according to Genebank accession number AF103796. HPRD:04783
Approx. Protein Concentrations
IgG concentration 0.25 mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Guarantee
Guaranteed until date of expiry. Please see product label.

More Information

UniProt
Q9UNQ0 Related reagents
Entrez Gene
ABCG2 Related reagents
Regulatory
For research purposes only

Applications of CD338 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Frozen
Western Blotting
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Human anti Mouse IgG2a:FITC HCA037F F 0.1 mg loader
Human anti Mouse IgG2a:HRP HCA037P E 0.1 mg loader
Goat anti Mouse IgG (H/L):Alk. Phos. (Multi Species Adsorbed) STAR117A E WB 0.5 mg loader
Goat anti Mouse IgG (H/L):DyLight®488 (Multi Species Adsorbed) STAR117D488GA F IF 0.1 mg loader
Goat anti Mouse IgG (H/L):DyLight®680 (Multi Species Adsorbed) STAR117D680GA F WB 0.1 mg loader
Goat anti Mouse IgG (H/L):DyLight®800 (Multi Species Adsorbed) STAR117D800GA F IF WB 0.1 mg loader
Goat anti Mouse IgG (H/L):FITC (Multi Species Adsorbed) STAR117F F 0.5 mg loader
Goat anti Mouse IgG (H/L):HRP (Multi Species Adsorbed) STAR117P E WB 0.5 mg loader
Goat anti Mouse IgG (Fc):FITC STAR120F C F 1 mg loader
Goat anti Mouse IgG (Fc):HRP STAR120P E WB 1 mg loader
Rabbit F(ab')2 anti Mouse IgG:RPE STAR12A F 1 ml loader
Rabbit F(ab')2 anti Mouse IgG:HRP (Human Adsorbed) STAR13B C E P RE WB 1 mg loader
Goat anti Mouse IgG:FITC (Rat Adsorbed) STAR70 F 0.5 mg loader
Goat anti Mouse IgG:RPE (Rat Adsorbed) STAR76 F 1 ml loader
Goat anti Mouse IgG:HRP (Rat Adsorbed) STAR77 C E P 0.5 mg loader
Goat anti Mouse IgG/A/M:Alk. Phos. STAR87A C E WB 1 mg loader
Goat anti Mouse IgG/A/M:HRP (Human Adsorbed) STAR87P E 1 mg loader
Rabbit F(ab')2 anti Mouse IgG:Dylight®800 STAR8D800GA F IF WB 0.1 mg loader
Rabbit F(ab')2 anti Mouse IgG:FITC STAR9B F 1 mg loader

Product Specific References

References for CD338 antibody

  1. Maliepaard, M. et al. (2001) Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues.
    Cancer Res. 61 (8): 3458-64.
  2. Scheffer, G.L. et al. (2000) Breast cancer resistance protein is localized at the plasma membrane in mitoxantrone- and topotecan-resistant cell lines.
    Cancer Res. 60 (10): 2589-93.