CD30 antibody | G05-2D2
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E ResetMouse anti Human CD30
- Product Type
- Monoclonal Antibody
- Clone
- G05-2D2
- Isotype
- IgG1
- Specificity
- CD30
Antibody Quality and Performance Guarantee
| Mouse anti Human CD30 antibody, clone G05-2D2, recognizes CD30 also known as Tumor Necrosis Factor Receptor Super Family member 8, CD30L receptor and Ki-1 antigen. CD30 is a 120 kDa transmembrane glycoprotein that belongs to the tumor necrosis factor receptor superfamily. CD30 is expressed on small subsets of activated T and B lymphocytes and a range of lymphoid neoplasms (Weyden et al. 2017). Upon binding of its ligand CD30L, CD30 undergoes trimerization and recruits TNFR-associated factor (TRAF) and TRAF binding proteins generating a signaling complex which can then mediate MAPK and NFκB signaling (Weyden et al. 2017). In this way, CD30 signaling is able to regulate peripheral T cell responses, controls T cell survival, down regulates cytolitic capacity and regulates thymocyte survival (Muta & Podack 2013). The purified Mouse anti Human CD30 antibody, clone G05-2D2 (MCA62670GA) can be used as a capture antibody in a sandwich ELISA with the biotinylated Mouse anti Human CD30 antibody, clone D02-6E11 (MCA6271B) as the detection antibody. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Yes
- Immunogen
- E. coli derived recombinant human full length CD30 (Phe19-Lys595)
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Cell fusion between immunized BALB/c mouse spleen cells and mouse myeloma SP2/0
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
1.0 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse anti Human CD30:Biotin | MCA6271B | E | 0.1 mg |
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| Description | Mouse anti Human CD30:Biotin | ||||||
- Synonyms
- TNFRSF8
- UniProt
- P28908
- Entrez Gene
- TNFRSF8
- GO Terms
- GO:0005886 plasma membrane
- GO:0016021 integral to membrane
- GO:0005737 cytoplasm
- GO:0008285 negative regulation of cell proliferation
- GO:0042535 positive regulation of tumor necrosis factor biosynthetic process
- GO:0043065 positive regulation of apoptosis
- GO:0045556 positive regulation of TRAIL biosynthetic process
MCA6270GA
100005241
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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