CD23 antibody | 1B12
Mouse anti Human CD23 antibody, clone 1B12 recognizes the human CD23 cell surface antigen also known as FcƐRII (Fc epsilon Receptor II). CD23 is a 45 kDa glycoprotein that functions as a low affinity receptor for IgE.
CD23 is expressed by peripheral B lymphocytes, cells of B cell chronic lymphocytic leukaemia and upon EBV transformed lymphoblastoid cells.
CD23 is expressed by peripheral B lymphocytes, cells of B cell chronic lymphocytic leukaemia and upon EBV transformed lymphoblastoid cells.
Product Details
- Target Species
- Human
- Product Form
- Tissue Culture Supernatant - liquid
- Preservative Stabilisers
- Pack Size: 0.1 ml
0.09% Sodium Azide Pack Size: 1 ml0.09% Sodium Azide (NaN3) - Immunogen
- Recombinant human CD23.
- Fusion Partners
- Spleen cells from immunised mice were fused with cells of the mouse p3-NS1-Ag4-1 myeloma cell line
Storage Information
- Storage
- Pack Size: 0.1 mlStore at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.Pack Size: 1 mlStore at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Shelf Life
- Please see label for expiry date
More Information
- UniProt
- P06734 Related reagents
- Entrez Gene
- FCER2 Related reagents
- GO Terms
- GO:0005576 extracellular region
- GO:0004872 receptor activity
- GO:0005887 integral to plasma membrane
- GO:0005178 integrin binding
- GO:0005529 sugar binding
- GO:0019863 IgE binding
- GO:0051000 positive regulation of nitric-oxide synthase activity
- GO:0051712 positive regulation of killing of cells of other organism
- GO:0051773 positive regulation of nitric-oxide synthase 2 biosynthetic process
- Regulatory
- For research purposes only
Applications of CD23 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry | |||
| Immunohistology - Frozen | 1/20 | 1/40 | |
| Immunohistology - Paraffin 1 | 1/20 | 1/40 |
- 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- Histology Positive Control Tissue
- Tonsil
Copyright © 2018 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
Negative Isotype Controls Available
| Description | Product Code | Pack Size | Applications | List Price | Quantity |
|---|---|---|---|---|---|
| Mouse IgG1 Negative Control | MCA928 | 100 Tests | F |
Product Specific References
References for CD23 antibody
-
Watson, P. et al. (2000) Monoclonal antibodies recognizing CD5, CD10 and CD23 in formalin-fixed, paraffin-embedded tissue: production and assessment of their value in the diagnosis of small B-cell lymphoma.
Histopathology. 36: 145-50. -
Steiniger, B. et al. (2011) The follicular dendritic cell network in secondary follicles of human palatine tonsils and spleens.
Histochem Cell Biol. 135: 327-36. -
Yoshida, S. et al. (2005) Primary breast diffuse large B-cell lymphoma shows a non-germinal center B-cell phenotype.
Mod Pathol. 18: 398-405. -
Tasaki, K. et al. (2007) CD5-positive mucosa-associated lymphoid tissue (MALT) lymphoma of ocular adnexal origin: usefulness of fluorescence in situ hybridization for distinction between mantle cell lymphoma and MALT lymphoma.
Pathol Int. 57: 101-7.
