Mouse anti Human CD23 antibody, clone 1B12 recognizes the human CD23 cell surface antigen also known as FcƐRII (Fc epsilon Receptor II). CD23 is a 45 kDa glycoprotein that functions as a low affinity receptor for IgE.
CD23 is expressed by peripheral B lymphocytes, cells of B cell chronic lymphocytic leukaemia and upon EBV transformed lymphoblastoid cells.
- Target Species
- Product Form
- Tissue Culture Supernatant - liquid
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Recombinant human CD23.
- Fusion Partners
- Spleen cells from immunised mice were fused with cells of the mouse p3-NS1-Ag4-1 myeloma cell line
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
- Guaranteed until date of expiry. Please see product label.
- Entrez Gene
- GO Terms
integral to plasma membrane
positive regulation of nitric-oxide synthase activity
positive regulation of killing of cells of other organism
positive regulation of nitric-oxide synthase 2 biosynthetic process
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of CD23 antibody
|Immunohistology - Frozen
|Immunohistology - Paraffin 1
- 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- Histology Positive Control Tissue
Copyright © 2021 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
Negative Isotype Controls Available
Product Specific References
References for CD23 antibody
Watson, P. et al. (2000) Monoclonal antibodies recognizing CD5, CD10 and CD23 in formalin-fixed, paraffin-embedded tissue: production and assessment of their value in the diagnosis of small B-cell lymphoma.
Histopathology. 36: 145-50.
Steiniger, B. et al. (2011) The follicular dendritic cell network in secondary follicles of human palatine tonsils and spleens.
Histochem Cell Biol. 135: 327-36.
Yoshida, S. et al. (2005) Primary breast diffuse large B-cell lymphoma shows a non-germinal center B-cell phenotype.
Mod Pathol. 18: 398-405.
Tasaki, K. et al. (2007) CD5-positive mucosa-associated lymphoid tissue (MALT) lymphoma of ocular adnexal origin: usefulness of fluorescence in situ hybridization for distinction between mantle cell lymphoma and MALT lymphoma.
Pathol Int. 57: 101-7.
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