CD172a antibody | 4C7
Mouse anti Human CD172 antibody, clone 4C7 recognizes human Tyrosine-protein phosphatase non-receptor type substrate 1, also known as Brain Ig-like molecule with tyrosine-based activation motifs, CD172 antigen-like family member A, Inhibitory receptor SHPS-1, Macrophage fusion receptor, MyD-1 antigen, Signal-regulatory protein alpha-1, Signal-regulatory protein alpha-2, Signal-regulatory protein alpha-3, p84 or CD172a. CD172a is a 474 amino acid, with an additional 30 amino acid signal peptide ~48 kDa single pass type 1 transmembrane glycoprotein and cell surface receptor for CD47.
Three isoforms of CD172a produced by alternative splicing have been described. Mouse anti Human CD172 antibody, clone 4C7 binds the canonical isoform 1. Binding to other isoforms has not been established (UniProt : P78324).
Three isoforms of CD172a produced by alternative splicing have been described. Mouse anti Human CD172 antibody, clone 4C7 binds the canonical isoform 1. Binding to other isoforms has not been established (UniProt : P78324).
Product Details
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Immunogen
- Recombinant protein corresponding to aa 28-508 of human CD172a.
- Approx. Protein Concentrations
- Ig concentration 0.5 mg/ml
- Fusion Partners
- Spleen cells from BALB/c mice were fused with cells from the Sp2/0 myeloma cell line.
Storage Information
- Storage
- Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Shelf Life
- 18 months from date of despatch.
More Information
- UniProt
- P78324 Related reagents
- Entrez Gene
- SIRPA Related reagents
- Regulatory
- For research purposes only
Applications of CD172a antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunofluorescence | 0.1 | 10 ug/ml | |
| Western Blotting | 0.1 | 10 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available
