Mouse anti Human CD167 antibody recognizes CD167, also known as CD167 antigen-like family member A, PTK3A protein tyrosine kinase 3A, cell adhesion kinase, epithelial discoidin domain-containing receptor 1 or DDR1, mammary carcinoma kinase 10, protein-tyrosine kinase RTK-6, tyrosine kinase DDR and tyrosine-protein kinase CAK.

Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases mostly regulate cell growth, differentiation and metabolism. CD167 belongs to a subfamily of tyrosine kinase receptors activated by various types of collagen with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for CD167 (provided by RefSeq, Feb 2011).

Mouse anti Human CD167 antibody detects a band of 125 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000