CD158b antibody | 190IIC311
CD158b is primarily expressed on a subset of natural killer (NK) cells and functions as a receptor that binds to HLA class I molecules, including HLA-Cw3 and related HLA-C alleles.
Mouse anti Human CD158b, clone 190IIC311 reacts with an extracellular domain of KIR2DL3 but does not recognize related KIR2DL family members KIR2DL1 and KIR2DS4.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide
- Carrier Free
- Recombinant human KIR2DL3.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised Balb/c mice were fused with cells of the mouse P3-X63-Ag8.653 myeloma cell line.
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- P43628 Related reagents
- Entrez Gene
- KIR2DL3 Related reagents
- GO Terms
- GO:0005515 protein binding
- GO:0003823 antigen binding
- GO:0004872 receptor activity
- GO:0005887 integral to plasma membrane
- GO:0006955 immune response
- GO:0050776 regulation of immune response
- For research purposes only
Applications of CD158b antibody
|Application Name||Verified||Min Dilution||Max Dilution|
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Secondary Antibodies Available
Negative Isotype Controls Available
|Description||Product Code||Applications||Pack Size||List Price||Quantity|
|Mouse IgG2a Negative Control||MCA929||F||100 Tests|
Product Specific References
References for CD158b antibody
Shin JS et al. (1999) Monoclonal antibodies with various reactivity to p58 killer inhibitory receptors.
Hernández-Caselles, T. et al. (2006) A study of CD33 (SIGLEC-3) antigen expression and function on activated human T and NK cells: two isoforms of CD33 are generated by alternative splicing.
J Leukoc Biol. 79: 46-58.