CD11b antibody | OTI2D11
Filter by Application:
WB ResetMouse anti CD11b
- Product Type
- PrecisionAb Monoclonal
- Clone
- OTI2D11
- Isotype
- IgG1
- Format
- Purified
- Specificity
- CD11b
Antibody Quality and Performance Guarantee
| Mouse anti Human CD11b antibody, clone OTI2D11 recognizes CD11b also known as integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, cell surface glycoprotein MAC-1 subunit alpha, leukocyte adhesion receptor MO1, macrophage antigen alpha polypeptide or neutrophil adherence receptor alpha-M subunit. The ITGAM gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for ITGAM (provided by RefSeq, Mar 2009). Mouse anti Human CD11b antibody, clone OTI2D11 detects a band of 170 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
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- Target Species
- Human
- Western Blotting
- Anti CD11b detects a band of approximately 170 kDa in TF-1 cell lysate.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography from ascites.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
50% Glycerol - Immunogen
- Full length recombinant protein of human CD11b produced in HEK293T cells
- Regulatory
- For research purposes only.
- Guarantee
- 12 months from date of despatch.
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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| List Price | Your Price | ||||||
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| Description | Goat anti Mouse IgG (H/L):HRP | ||||||
- UniProt
- P11215
- Entrez Gene
- ITGAM
- GO Terms
- GO:0007596 blood coagulation
- GO:0004872 receptor activity
- GO:0008305 integrin complex
- GO:0007229 integrin-mediated signaling pathway
VMA00481
160801
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