CD107b antibody | H4B4
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|Mouse anti Human CD107b, clone H4B4 recognizes CD107b. CD107b (also known as LAMP-2) is a major component in lysosomal membranes. It is composed of a polypeptide core of approximately 45 kDa but normally migrates between 100-120 kDa due to high levels of glycosylation (Fukuda, M. et al, 1988).
Clone H4B4 has been reported to suitable for use in Transmission Electron Microscopy (Mane, S. et al, 1988).
- Target Species
- Species Cross-Reactivity
Target Species Cross Reactivity Mouse Rat
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide (NaN3)
0.2% Bovine Serum Albumin
- Human PBMCs
- Max Ex/Em
Fluorophore Excitation Max (nm) Emission Max (nm) FITC 490 525
- For research purposes only
- Guaranteed for 12 months from the date of despatch or until the date of expiry, whichever comes first. Please see label for expiry date.
This product should be stored undiluted. This product is photosensitive and should be protected from light.
|Application Name||Verified||Min Dilution||Max Dilution|
- Flow Cytometry
- Use 4ul of the undiluted reagent to label 1x106 cells in 100ul
References for CD107b antibody
Fukuda, M. et al. (1988) Cloning of cDNAs encoding human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Comparison of their deduced amino acid sequences.
J Biol Chem. 263 (35): 18920-8.
Mane, S.M. et al. (1989) Purification and characterization of human lysosomal membrane glycoproteins.
Arch Biochem Biophys. 268 (1): 360-78.
- Entrez Gene
- GO Terms
- GO:0005886 plasma membrane
- GO:0002576 platelet degranulation
- GO:0016021 integral to membrane
- GO:0005624 membrane fraction
- GO:0005765 lysosomal membrane
- GO:0005770 late endosome
- GO:0010008 endosome membrane
- GO:0030168 platelet activation
- GO:0031088 platelet dense granule membrane
- View More GO Terms
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