CD105 antibody | 2H6F11

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Mouse anti Human CD105

Product Type
Monoclonal Antibody
Clone
2H6F11
Isotype
IgG1
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
MCA5674 E F WB 0.2 mg
Mouse anti Human CD105 antibody, clone 2H6F11 recognizes the human CD105 cell surface antigen, a glycoprotein homodimer of ~95 kDa subunits.

CD105 is also known as endoglin, and is expressed by endothelial cells, activated monocytes and some leukemia cells.

Product Details

Target Species
Human
Product Form
Purified IgG - liquid
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
Approx. Protein Concentrations
IgG concentration 0.1mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
P17813 Related reagents
Entrez Gene
ENG Related reagents
GO Terms
GO:0001300 chronological cell aging
GO:0001569 patterning of blood vessels
GO:0001937 negative regulation of endothelial cell proliferation
GO:0001947 heart looping
GO:0003084 positive regulation of systemic arterial blood pressure
GO:0007155 cell adhesion
GO:0004888 transmembrane receptor activity
GO:0005024 transforming growth factor beta receptor activity
GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity
GO:0005114 type II transforming growth factor beta receptor binding
GO:0005534 galactose binding
GO:0005539 glycosaminoglycan binding
GO:0005615 extracellular space
GO:0005624 membrane fraction
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0050431 transforming growth factor beta binding
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
GO:0022009 central nervous system vasculogenesis
GO:0022617 extracellular matrix disassembly
GO:0030155 regulation of cell adhesion
GO:0030509 BMP signaling pathway
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030513 positive regulation of BMP signaling pathway
GO:0031953 negative regulation of protein autophosphorylation
GO:0034713 type I transforming growth factor beta receptor binding
GO:0042060 wound healing
GO:0042127 regulation of cell proliferation
GO:0042803 protein homodimerization activity
GO:0045449 regulation of transcription
GO:0048185 activin binding
GO:0048745 smooth muscle tissue development
GO:0048844 artery morphogenesis
GO:0048845 venous blood vessel morphogenesis
GO:0051001 negative regulation of nitric-oxide synthase activity
GO:0060326 cell chemotaxis
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0070022 transforming growth factor beta receptor complex
GO:0070483 detection of hypoxia
Regulatory
For research purposes only

Applications of CD105 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Flow Cytometry Neat
Western Blotting
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Flow Cytometry
Use 20ul of the suggested working dilution to label 106 cells in 100ul.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Human anti Mouse IgG1:HRP HCA036P 0.1 mg E
Goat anti Mouse IgG (H/L):Alk. Phos. (Multi Species Adsorbed) STAR117A 0.5 mg E WB
Goat anti Mouse IgG (H/L):DyLight®488 (Multi Species Adsorbed) STAR117D488GA 0.1 mg F IF
Goat anti Mouse IgG (H/L):DyLight®549 (Multi Species Adsorbed) STAR117D549GA 0.1 mg F IF WB
Goat anti Mouse IgG (H/L):DyLight®649 (Multi Species Adsorbed) STAR117D649GA 0.1 mg F IF
Goat anti Mouse IgG (H/L):DyLight®680 (Multi Species Adsorbed) STAR117D680GA 0.1 mg F WB
Goat anti Mouse IgG (H/L):DyLight®800 (Multi Species Adsorbed) STAR117D800GA 0.1 mg F IF WB
Goat anti Mouse IgG (H/L):FITC (Multi Species Adsorbed) STAR117F 0.5 mg F
Goat anti Mouse IgG (H/L):HRP (Multi Species Adsorbed) STAR117P 0.5 mg E WB
Goat anti Mouse IgG (Fc):FITC STAR120F 1 mg C F
Goat anti Mouse IgG (Fc):HRP STAR120P 1 mg E WB
Rabbit F(ab')2 anti Mouse IgG:RPE STAR12A 1 ml F
Rabbit F(ab')2 anti Mouse IgG:HRP (Human Adsorbed) STAR13B 1 mg C E P RE WB
Goat anti Mouse IgG:FITC (Rat Adsorbed) STAR70 0.5 mg F
Goat anti Mouse IgG:RPE (Rat Adsorbed) STAR76 1 ml F
Goat anti Mouse IgG:HRP (Rat Adsorbed) STAR77 0.5 mg C E P
Goat anti Mouse IgG/A/M:Alk. Phos. STAR87A 1 mg C E WB
Goat anti Mouse IgG/A/M:HRP (Human Adsorbed) STAR87P 1 mg E
Rabbit F(ab')2 anti Mouse IgG:Dylight®800 STAR8D800GA 0.1 mg F IF WB
Rabbit F(ab')2 anti Mouse IgG:FITC STAR9B 1 mg F

Negative Isotype Controls Available

Description Product Code Pack Size Applications List Price Quantity
Mouse IgG1 Negative Control MCA928 100 Tests F

Product Specific References

References for CD105 antibody

  1. Luque, A. et al. (1997) The use of recombinant vaccinia virus to generate monoclonal antibodies against the cell-surface glycoprotein endoglin.
    FEBS Lett. 413 (2): 265-8.