CCL27 antibody | B05-10H9
Mouse anti Human CCL27:Biotin
- Product Type
- Monoclonal Antibody
- Clone
- B05-10H9
- Isotype
- IgG1
- Specificity
- CCL27
Antibody Quality and Performance Guarantee
| Mouse anti Human CCL27 antibody, clone B05-10H9 recognizes C-C motif chemokine 27, also known as CTACK, ESkine, ILC, and SCYA27. CCL27 is a C-C motif chemokine. CCR10 is the only known receptor for CCL27, and is expressed in normal skin (Mao et al. 2018). CCL27 is able to attract a subset of memory / effector T cells from peripheral blood to specific locations on the skin (Wang et al. 2018). CCL27 plays a role in T cell mediated skin inflammation, and high levels have been found in patients with psoraisis and atopic dermatitis. Upregulation of CCL27 has been identified in patients with myeloma, and is correlated with poor overall survival (Thangavadivel et al. 2016). CCL27 is secreted by primary tumor cells with high metastatic potential and is able to attract lymphatic endothelial cells, a crucial process during lymphangiogenesis (Karnezis et al. 2019). This biotinylated Mouse anti Human CCL27 antibody, clone B05-10H9 (MCA6185B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human CCL27 antibody, clone A01-2H4 (MCA6184GA) as the capture antibody. |
- Target Species
- Human
- Product Form
- Purified IgG conjugated to Biotin - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin - Immunogen
- E. coli derived recombinant human full length CCL27 (Phe25-Gly112)
- Approx. Protein Concentrations
- IgG concentration 0.1 mg/ml
- Fusion Partners
- Cell fusion between immunized BALB/c mouse spleen cells and mouse myeloma SP2/0
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
1.0 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse anti Human CCL27 | MCA6184GA | E | 0.1 mg |
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| Description | Mouse anti Human CCL27 | ||||||
- Synonyms
- Ctack
- UniProt
- Q9Y4X3
- Entrez Gene
- CCL27
- GO Terms
- GO:0005615 extracellular space
- GO:0006935 chemotaxis
- GO:0006955 immune response
- GO:0007267 cell-cell signaling
- GO:0008009 chemokine activity
MCA6185B
100005232
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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