CCL13 antibody | B16-3D8

Mouse anti Human CCL13:Biotin

Product Type
Monoclonal Antibody
Clone
B16-3D8
Isotype
IgG1
Specificity
CCL13

Product Code Applications Pack Size List Price Your Price Qty
MCA6177B
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E 0.1 mg loader
List Price Your Price
loader
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Mouse anti Human CCL13 antibody, clone B16-3D8, recognizes CCL13, a member of the CC family of cytokines. CCL13, also known as MCP-4, is a 98 amino acid (aa) precursor protein which contains a 23 aa hydrophobic signal peptide that is cleaved to the mature form of the protein which is 75aa protein (8kDa). CCL13 is a chemoattractant for various cells including monocytes, T cells, immature dendritic cells and eosinophils (Entiquez & Garcia-Zepeda 2013). It has also been associated with various inflammatory diseases including asthma, arthritis, atherosclerosis and multiple sclerosis (Procaccini et al. 2015). CCL13 can bind to several chemokine receptors (CCR1, CCR2 and CCR3) to elicit chemoattractant responses. It is also known to induce degranulation of eosinophils and the secretion of pro-inflammatory cytokines.

This biotinylated Mouse anti Human CCL13 antibody, clone B16-3D8 (MCA6177B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human CCL13 antibody, clone B06-1G9 (MCA6176GA) as the capture antibody.

Target Species
Human
Product Form
Purified IgG conjugated to Biotin - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
Immunogen
E. coli derived recombinant human full length CCL13 (Phe17-Thr98)
Approx. Protein Concentrations
IgG concentration 0.1 mg/ml
Fusion Partners
Cell fusion between immunized BALB/c mouse spleen cells and mouse myeloma SP2/0
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1.0 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Description Product Code Applications Pack Size List Price Your Price Quantity
Mouse anti Human CCL13 MCA6176GA E 0.1 mg loader
List Price Your Price
loader
Description Mouse anti Human CCL13

Synonyms
MCP-4
UniProt
Q99616
Entrez Gene
CCL13
GO Terms
GO:0004871 signal transducer activity
GO:0005615 extracellular space
GO:0006874 cellular calcium ion homeostasis
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007267 cell-cell signaling
GO:0008009 chemokine activity
View more products with CCL13 specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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