Carcinoembryonic Antigen antibody | Arcitumomab

Human anti Carcinoembryonic Antigen (Arcitumomab Biosimilar)

Product Type
Monoclonal Antibody
Clone
Arcitumomab
Isotype
IgG1
Specificity
Carcinoembryonic Antigen

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MCA6094
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Human anti carcinoembryonic antigen (CEA) antibody is a research grade biosimilar of the monoclonal diagnostic antibody drug arcitumomab. This product is supplied in a research grade format, i.e. in PBS buffer with preservative, it is not manufactured or formulated in the same way as the therapeutic reference product. A preservative free version is available on request.

This product is a recombinant human IgG1 kappa antibody with variable regions from the hybridoma arcitumomab.

Human anti carcinoembryonic antigen antibody recognizes CEA, a glycoprotein involved in cell adhesion. Overexpression of CEA is associated with a number of gastrointestinal tract carcinomas. The diagnostic drug arcitumomab was used in the diagnosis of recurrent or metastatic colorectal carcinoma.

This product is for research use only, it is NOT FOR DIAGNOSTIC USE.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Human IgG1 kappa recombinant antibody - liquid
Preparation
Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Proclin 300
Immunogen
Human carcinoembryonic antigen
Purity
>98% by SDS PAGE
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunofluorescence
Immunohistology - Paraffin
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Licensed Use
For in vitro research purposes only. Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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