Calcitonin antibody | Cn 44 (BGN/1199/44)
Mouse anti Human calcitonin antibody, clone Cn 44 recognizes human calcitonin, a 32 amino acid peptide hormone, produced and secreted by parafollicular cells (C cells) within the thyroid. It acts to reduce plasma calcium levels opposing the effects of parathyroid hormone.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide (NaN3)
- Carrier Free
- Native, intact human calcitonin.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- Shelf Life
- 18 months from date of despatch.
- P01258 Related reagents
- Entrez Gene
- CALCA Related reagents
- GO Terms
- GO:0002548 monocyte chemotaxis
- GO:0005179 hormone activity
- GO:0005615 extracellular space
- GO:0007566 embryo implantation
- GO:0016481 negative regulation of transcription
- GO:0031716 calcitonin receptor binding
- GO:0032147 activation of protein kinase activity
- GO:0045762 positive regulation of adenylate cyclase activity
- GO:0045779 negative regulation of bone resorption
- GO:0051482 elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger
- For research purposes only
Applications of Calcitonin antibody
|Application Name||Verified||Min Dilution||Max Dilution|
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
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