Beta Arrestin-2 antibody | 4D2
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WB IF ResetMouse anti Human Beta Arrestin-2:Preservative Free
- Product Type
- Monoclonal Antibody
- Clone
- 4D2
- Isotype
- IgG2a
- Specificity
- Beta Arrestin-2
Antibody Quality and Performance Guarantee
| Mouse anti Human beta arrestin-2 antibody, clone 4D2 recognizes human beta arrestin-2, a 409 amino acid ~45 kDa intracellular protein involved in regulation of cellular responses to GPCR signaling. Multiple isoforms of beta arrestin-2 produced by alternative splicing have been described. Mouse anti Human beta arrestin-2 antibody, clone 4D2 binds to the canonical isoform. Isoforms 2 and 3 contain inclusions within the immunogen sequence used to generate clone 4D2 and binding to these isoforms has not been assessed. Isoforms 4 and 5 both have the complete unmodified immunogen sequence and Mouse anti Human beta arrestin-2 antibody, clone 4D2 would therefore be expected to bind these isoforms (UniProt : P32121). |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Immunogen
- Recombinant protein corresponding to aa 300-410 of human beta arrestin-2.
- Approx. Protein Concentrations
- Ig concentration 0.5 mg/ml
- Fusion Partners
- Spleen cells from BALB/c mice were fused with cells from the Sp2/0 myeloma cell line.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunofluorescence |  |
0.1 | 10 ug/ml |
| Western Blotting | |
0.1 | 10 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- RRID
- AB_2243079
- UniProt
- P32121
- Entrez Gene
- ARRB2
MCA5314Z
040815
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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