Beta Arrestin-2 antibody | 4D2

Mouse anti Human Beta Arrestin-2:Preservative Free

Product Type
Monoclonal Antibody
Clone
4D2
Isotype
IgG2a
Specificity
Beta Arrestin-2

Product Code Applications Pack Size List Price Your Price Qty
MCA5314Z
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
IF WB 0.1 mg loader
List Price Your Price
loader
Search for Batch Specific Datasheets

Mouse anti Human beta arrestin-2 antibody, clone 4D2 recognizes human beta arrestin-2, a 409 amino acid ~45 kDa intracellular protein involved in regulation of cellular responses to GPCR signaling.

Multiple isoforms of beta arrestin-2 produced by alternative splicing have been described. Mouse anti Human beta arrestin-2 antibody, clone 4D2 binds to the canonical isoform. Isoforms 2 and 3 contain inclusions within the immunogen sequence used to generate clone 4D2 and binding to these isoforms has not been assessed. Isoforms 4 and 5 both have the complete unmodified immunogen sequence and Mouse anti Human beta arrestin-2 antibody, clone 4D2 would therefore be expected to bind these isoforms (UniProt : P32121).

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein A from ascites
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
None present
Immunogen
Recombinant protein corresponding to aa 300-410 of human beta arrestin-2.
Approx. Protein Concentrations
Ig concentration 0.5 mg/ml
Fusion Partners
Spleen cells from BALB/c mice were fused with cells from the Sp2/0 myeloma cell line.
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunofluorescence 0.1 10 ug/ml
Western Blotting 0.1 10 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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RRID
AB_2243079
UniProt
P32121
Entrez Gene
ARRB2
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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