BAG2 antibody | AB01/3G9

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Mouse anti BAG2

Product Type
PrecisionAb Monoclonal
Clone
AB01/3G9
Isotype
IgG1
Format
Purified
Product Code Applications Pack Size List Price Quantity
VMA00928
Datasheet
WB
SDS
100 µl loader

Mouse anti BAG2 antibody recognizes BAG family molecular chaperone regulator 2, also known as Bcl-2-associated athanogene 2.

BAG2 is a member of the BAG family. These proteins interact with the molecular chapherone HSP70, dictating HSP70 interactions with client proteins and apoptosis. BAG2 also interacts with a range of other molecules, regulating various cellular functions (Qin et al. 2016). BAG2 phosphorylation by MAPKAP kinase 2 is part of the p38 signaling pathway in response to extracellular stress (Ueda et al. 2004). BAG2 is induced by proteasome inhibitors and appears to promote apoptosis in cancer cells (Wang et al. 2008). BAG2 has also been implicated in Parkinson's disease (Fukuzono et al. 2016) and Alzheimer's disease (de Paula et al. 2016). Recently, studies have found a role of BAG2 in successful infection by simian virus 40 (Dupzyk and Tsai, 2018).

Product Details

Target Species
Human
Western Blotting
Mouse anti BAG2 detects a band of approximately 24 kDa in HeLa cell lysates
Product Form
Purified IgG - Liquid
Preparation
Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
Immunogen
E. coli-derived recombinant protein of amino acids 1-211 of human BAG2
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Fusion Partners
Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line

Storage Information

Storage
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
Guarantee
12 months from date of despatch

More Information

UniProt
O95816
Entrez Gene
BAG2
GO Terms
GO:0005515 protein binding
GO:0006457 protein folding
GO:0006915 apoptosis
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory
For research purposes only

Applications of BAG2 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml

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