AXL Receptor Tyrosine Kinase antibody
Encoded by the AXL gene, the AXL oncogene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. It possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). AXL may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of AXL (provided by RefSeq, Jul 2013).
Mouse anti Human AXL receptor tyrosine kinase antibody detects a band of 138 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
- Target Species
- Western Blotting
- Anti AXL receptor tyrosine kinase detects a band of approximately 138 kDa in HeLa cell lysates
- Product Form
- Purified IgG - liquid
- Mouse monoclonal antibody prepared by affinity chromatography on Protein G from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Purified recombinant extracellular fragment of human AXL receptor tyrosine kinase fused with hIgGFc tag expressed in the HEK293 cell line
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- As supplied, 12 months from date of despatch.
- P30530 Related reagents
- Entrez Gene
- AXL Related reagents
- GO Terms
- GO:0004714 transmembrane receptor protein tyrosine kinase activity
- GO:0005887 integral to plasma membrane
- GO:0005524 ATP binding
- GO:0006468 protein phosphorylation
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- For research purposes only
Applications of AXL Receptor Tyrosine Kinase antibody
|Application Name||Verified||Min Dilution||Max Dilution|
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
Secondary Antibodies Available
|Description||Product Code||Applications||Pack Size||List Price||Quantity|
|Goat anti Mouse IgG (H/L):HRP||STAR207P||WB||2 ml|
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