ATF1 antibody | AB01/1D8
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WB ResetMouse anti ATF1
- Product Type
- PrecisionAb Monoclonal
- Clone
- AB01/1D8
- Isotype
- IgG2a
- Format
- Purified
- Specificity
- ATF1
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| Mouse anti ATF1 antibody recognizes cyclic AMP-dependent transcription factor ATF-1, also known as TREB36. ATF1 is a basic region-leucine zipper transcription factor belonging to the cAMP response element-binding protein family. In embryonic stem cells (ESCs), ATF1 is a regulator of pluripotency and ATF1 knockdown has been shown to up-regulate neuroectoderm genes (Yang et al. 2019). Gene fusions between ATF1 and EWSR1 have been described in a range of neoplasms (Thway and Fisher 2012). ATF1 functions as an oncogene in colorectal cancer and facilitates proliferation by affecting apoptosis (Tian et al. 2019). |
|
- Target Species
- Human
- Western Blotting
- Mouse anti ATF1 antibody detects a band of approximately 37 kDa in HEK293 cell lysates
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - Liquid
- Preparation
- Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
- Immunogen
- E. coli-derived recombinant protein of amino acids 1-271 of human ATF1
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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| List Price | Your Price | ||||||
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| Description | Goat anti Mouse IgG (H/L):HRP | ||||||
- UniProt
- P18846
- Entrez Gene
- ATF1
- GO Terms
- GO:0002755 MyD88-dependent toll-like receptor signaling pathway
- GO:0002756 MyD88-independent toll-like receptor signaling pathway
- GO:0008063 Toll signaling pathway
- GO:0034130 toll-like receptor 1 signaling pathway
- GO:0034134 toll-like receptor 2 signaling pathway
- GO:0034138 toll-like receptor 3 signaling pathway
- GO:0034142 toll-like receptor 4 signaling pathway
- GO:0045087 innate immune response
- GO:0048011 nerve growth factor receptor signaling pathway
- View More GO Terms
- GO:0051403 stress-activated MAPK cascade
View more products with ATF1 specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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