Apolipoprotein A1 antibody | G2
Mouse anti Human Apolipoprotein A1, clone G2 reacts with both free human Apo-A1 and High Density Lipoprotein (HDL) bearing Apo-A1, but does not cross-react with ApoE, ApoB or Albumin.
- Target Species
- Product Form
- Purified IgG - lyophilised
- Reconstitute with 1.0ml distilled water
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
- Purified IgG prepared by affinity chromatography on Protein A from ascites
- Buffer Solution
- 0.01M Sodium Phosphate
0.01M Sodium Borate
0.15M Sodium Chloride
- Preservative Stabilisers
- 1% Dextran
- Native Apolipoprotein-A1 from human plasma
- Prior to reconstitution store at +4oC.
After reconstitution store at -20oC.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody.
- Guaranteed until date of expiry. Please see product label.
- P02647 Related reagents
- Entrez Gene
- APOA1 Related reagents
- GO Terms
- GO:0005886 plasma membrane
- GO:0001540 beta-amyloid binding
- GO:0002576 platelet degranulation
- GO:0002740 negative regulation of cytokine secretion involved in immune response
- GO:0005543 phospholipid binding
- GO:0005788 endoplasmic reticulum lumen
- GO:0030141 stored secretory granule
- GO:0030139 endocytic vesicle
- GO:0006656 phosphatidylcholine biosynthetic process
- GO:0007186 G-protein coupled receptor protein signaling pathway
- GO:0042802 identical protein binding
- GO:0010873 positive regulation of cholesterol esterification
- GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling
- GO:0015485 cholesterol binding
- GO:0050821 protein stabilization
- GO:0017127 cholesterol transporter activity
- GO:0019899 enzyme binding
- GO:0030168 platelet activation
- GO:0032488 Cdc42 protein signal transduction
- GO:0033344 cholesterol efflux
- GO:0033700 phospholipid efflux
- GO:0034191 apolipoprotein A-I receptor binding
- GO:0034361 very-low-density lipoprotein particle
- GO:0034366 spherical high-density lipoprotein particle
- GO:0034375 high-density lipoprotein particle remodeling
- GO:0034380 high-density lipoprotein particle assembly
- GO:0034384 high-density lipoprotein particle clearance
- GO:0042632 cholesterol homeostasis
- GO:0043691 reverse cholesterol transport
- GO:0050713 negative regulation of interleukin-1 beta secretion
- GO:0051345 positive regulation of hydrolase activity
- GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity
- GO:0070508 cholesterol import
- GO:0070653 high-density lipoprotein particle receptor binding
- For research purposes only
Applications of Apolipoprotein A1 antibody
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Frozen||1/40|
- This antibody is suitable for coating microtitre plates in a sandwich ELISA using catalogue number 0650-0190 for detection.
Secondary Antibodies Available
Product Specific References
References for Apolipoprotein A1 antibody
Derbali, H. et al. (2010) Increased biglycan in aortic valve stenosis leads to the overexpression of phospholipid transfer protein via Toll-like receptor 2.
Am J Pathol. 176: 2638-45.
Mogilenko, D.A. et al. (2012) Endogenous apolipoprotein A-I stabilizes ATP-binding cassette transporter A1 and modulates Toll-like receptor 4 signaling in human macrophages.
FASEB J. 26: 2019-30.
Shavva, V.S. et al. (2016) PPARγ Represses Apolipoprotein A-I Gene but Impedes TNFα-Mediated ApoA-I Downregulation in HepG2 Cells.
J Cell Biochem. 117 (9): 2010-22.
Pingitore, P. et al. (2016) Identification and characterization of two novel mutations in the LPL gene causing type I hyperlipoproteinemia.
J Clin Lipidol. 10 (4): 816-23.
Berge, K.E. et al. (2014) Type 1 hyperlipoproteinemia due to a novel deletion of exons 3 and 4 in the GPIHBP1 gene.
Atherosclerosis. 234 (1): 30-3.
Botta, M. et al. (2019) Deciphering the role of V200A and N291S mutations leading to LPL deficiency.
Atherosclerosis. 282: 45-51.