Mouse anti Human Amyloid A antibody, clone SAA1 recognizes serum amyloid A, an apolipoprotein associated with high-density lipoprotein (HDL). It is produced by the liver and secreted during the acute phase of inflammation. Amyloid A proteins are involved in several processes, including transporting cholesterol to the liver, recruiting immune cell to sites of inflammation and inducing enzymes that degrade extracellular matrix. These proteins are implicated in disease such as amyloidosis, atherosclerosis and rheumatoid arthritis. Elevated serum levels may be associated with lung cancer.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Human recombinant amyloid A, conjugated to a carrier protein.
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Fusion Partners
- Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line.
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Amyloid A antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available