Alpha Fetoprotein antibody | 125.7A2
AFP is a ~70kD plasma protein found in fetuses over four weeks old, produced by the yolk sac and the fetal liver, with the highest concentration reached during the 12th to 16th week of gestation. AFP acts as a transport protein for various ligands such as bilirubin, fatty acids, steroids and heavy metals. After birth, plasma AFP levels drop rapidly with only trace amounts remaining in healthy adults. Changes in plasma levels of AFP have been documented in a variety of cancers including hepatocellular cancer (Sato et al. 1993).
Mouse anti Human alpha fetoprotein antibody, clone 125.7A2 shows <0.1% reactivity with human serum albumin and IgG. Strong expression of AFP has been noted in the hepatic cell line HepG2.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch
- P02771 Related reagents
- Entrez Gene
- AFP Related reagents
- GO Terms
- GO:0046872 metal ion binding
- GO:0006810 transport
- For research purposes only
Applications of Alpha Fetoprotein antibody
|Application Name||Verified||Min Dilution||Max Dilution|