Alpha 1 Antitrypsin antibody | 1AT10-105.10 (1AT)
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Mouse anti Human Alpha 1 Antitrypsin
- Product Type
- Monoclonal Antibody
- Clone
- 1AT10-105.10 (1AT)
- Isotype
- IgG2a
- Specificity
- Alpha 1 Antitrypsin
Antibody Quality and 
Unrivaled 
| Mouse anti Human alpha-1-antitrypsin antibody, clone 1AT10-105.10 recognises human alpha-1 antitrypsin, a serine protease inhibitor synthesized by the liver. Hereditary deficiency of this protein is associated with pulmonary emphysema and with liver disease, due to the loss of inhibition of neutrophil elastase activity. Mouse anti Human alpha-1-antitrypsin antibody, clone 1AT10-105.10 shows minimal reactivity with other serum proteins including alpha-1-antichymotrypsin. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Immunogen
- Purified human serum alpha-1-antitrypsin
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
References for Alpha 1 Antitrypsin antibody
-
Comunale, M.A. et al. (2010) Linkage specific fucosylation of alpha-1-antitrypsin in liver cirrhosis and cancer patients: implications for a biomarker of hepatocellular carcinoma.
PLoS One. 5 (8): e12419.
View more products with Alpha 1 Antitrypsin specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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