AKR1B1 antibody | CPTC28
AKR1B1 gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for AKR1B1. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database (provided by RefSeq, Feb 2009).
Mouse anti Human AKR1B1 antibody detects a band of 36 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
- Target Species
- Western Blotting
- Anti AKR1B1 detects a band of approximately 36 kDa in HEK293 cell lysates
- Species Cross-Reactivity
Target Species Cross Reactivity Mouse Rat
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Mouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Recombinant protein of human AKR1B1
- Instructions For Use
- Please refer to the PrecisionAb western blotting protocol. For additional information on secondary antibody dilution and exposure time see product web page.
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- As supplied, 12 months from date of despatch.
- P15121 Related reagents
- Entrez Gene
- AKR1B1 Related reagents
- GO Terms
- GO:0009055 electron carrier activity
- GO:0005515 protein binding
- GO:0004032 aldehyde reductase activity
- GO:0005829 cytosol
- GO:0005615 extracellular space
- GO:0005634 nucleus
- GO:0005975 carbohydrate metabolic process
- GO:0055114 oxidation-reduction process
- GO:0006700 C21-steroid hormone biosynthetic process
- GO:0006950 response to stress
- PrecisionAb™ is a trademark of Bio-Rad Laboratories.
- For research purposes only
Applications of AKR1B1 antibody
|Application Name||Verified||Min Dilution||Max Dilution|
PrecisionAb antibodies have been extensively validated for the western blot application. The antibody has been validated at the suggested dilution. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.
Secondary Antibodies Available
|Description||Product Code||Pack Size||Applications||List Price||Quantity|
|Goat anti Mouse IgG (H/L):HRP||STAR207P||2 ml||WB|
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