AKR1B1 antibody | CPTC28

100% Secure


Mouse anti AKR1B1

Product Type
PrecisionAb Monoclonal
Clone
CPTC28
Isotype
IgG1
Format
Purified
Product Code Applications Pack Size List Price Quantity
VMA00554
Datasheet
WB
MSDS
100 µl loader

Mouse anti Human AKR1B1 antibody recognizes the aldose reductase, also known as Lii5-2 CTCL tumor antigen, aldehyde reductase 1, aldo-keto reductase family 1 member B1, ADR, or low Km aldose reductase.

AKR1B1 gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for AKR1B1. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database (provided by RefSeq, Feb 2009).

Mouse anti Human AKR1B1 antibody detects a band of 36 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti AKR1B1 detects a band of approximately 36 kDa in HEK293 cell lysates
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Recombinant protein of human AKR1B1

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Guarantee
As supplied, 12 months from date of despatch.

More Information

UniProt
P15121 Related reagents
Entrez Gene
AKR1B1 Related reagents
GO Terms
GO:0009055 electron carrier activity
GO:0005515 protein binding
GO:0004032 aldehyde reductase activity
GO:0005829 cytosol
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005975 carbohydrate metabolic process
GO:0055114 oxidation-reduction process
GO:0006700 C21-steroid hormone biosynthetic process
GO:0006950 response to stress
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of AKR1B1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml

Western Blotting without Trial and Error: Use PrecisionAb Antibodies

Watch how PrecisionAb Validated Western Blotting Antibodies are defining a new standard of quality that you can trust to deliver superior results and reproducibility in western blotting.