ABCC1 antibody

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Anti ABCC1 Antibody (PrecisionAb Monoclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with ABCC1 antibody followed by detection with HRP conjugated Goat anti Mouse IgG (1/10,000, STAR207P) and visualized on the ChemiDoc MP with 41.5 second exposure. Arrow points to ABCC1 (molecular weight 172 kDa)

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Mouse anti ABCC1

Product Type: PrecisionAb Monoclonal
Isotype: IgG1
Format: Purified
Specificity: ABCC1

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Mouse anti Human ABCC1 antibody recognizes the multidrug resistance-associated protein 1, also known as ATP-binding cassette transporter variant ABCC1delta-ex13, ATP-binding cassette transporter variant ABCC1delta-ex13&14, ATP-binding cassette transporter variant ABCC1delta-ex25, ATP-binding cassette transporter variant ABCC1delta-ex25&26, LTC4 transporter and leukotriene C(4) transporter.

Encoded by the ABCC1 gene, multidrug resistance-associated protein 1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. It functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of ABCC1 have been described but their full-length nature is unknown (provided by RefSeq, Apr 2012).

Mouse anti Human ABCC1 antibody detects a band of 172 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti ABCC1 detects a band of approximately 172 kDa in HepG2 cell lysates.
Product Form: Purified IgG - liquid
Preparation: Mouse monoclonal antibody prepared by affinity chromatography on Protein G from tissue culture supernatant.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃).
Immunogen: Recombinant protein corresponding to amino acids 194-316 of human ABCC1 expressed in E. coli
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.