Microtubule Associated Protein tau antibody | 4F1

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Mouse anti Bovine Microtubule Associated Protein tau

Product Type
Monoclonal Antibody
Clone
4F1
Isotype
IgG1
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
6242-0206 P WB 0.1 ml
Mouse anti Bovine microtubule associated protein tau antibody, clone 4F1 recognizes bovine microtubule associated protein tau. Tau proteins stabilize microtubules by interacting with tubulin, they are abundant in neurons in the central nervous system and are less common elsewhere. When tau proteins are defective and no longer stabilize microtubules properly, this can result in dementias, such as Alzheimer's disease (Kosik et al. 1986).

Mouse anti Bovine microtubule associated protein tau antibody, clone 4F1 reacts with tau in both the phosphorylated and non-phosphorylated form. It does not react with other microtubule associated proteins or tubulin.

Mouse anti Bovine microtubule associated protein tau antibody, clone 4F1 recognizes an epitope between amino acids 95 - 108 of bovine Tau.

Product Details

Target Species
Bovine
Species Cross-Reactivity
Target SpeciesCross Reactivity
Monkey
Human
Chicken
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Diluted Ascitic fluid - liquid
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09%Sodium Azide (NaN3)
Immunogen
Bovine microtubule associated proteins.
Approx. Protein Concentrations
1 mg/ml

Storage Information

Storage
Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
P29172 Related reagents
Entrez Gene
MAPT Related reagents
Regulatory
For research purposes only

Applications of Microtubule Associated Protein tau antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin
Western Blotting 1/250 1/1000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

Product Specific References

References for Microtubule Associated Protein tau antibody

  1. Watanabe, N. et al. (1992) Tau 2: a probe for a Ser conformation in the amino terminus of tau.
    J Neurochem. 58 (3): 960-6.