Mouse anti Bovine CD26, clone CACT114A
, recognizes bovine CD26 also known as DPP4 or dipeptidyl peptidase 4. Bovine CD26 is expressed in various cell types and participates in many biological activities such as the post-translational processing of chemokines (Proost et al. 2001
) and neuropeptides (Lambeir et al. 2001
), and in the regulation of degradation and inactivation of glucagon (Pospisilik et al. 2001
). CD26 also functions as a costimulatory molecule on activated T cells and is highly expressed on CD8+ natural killer cells in calves vaccinated against Mycobacterium avium paratuberculosis
(Park et al. 2015
- Target Species
- Product Form
- Concentrated tissue culture supernatant - liquid
- Concentrated tissue culture supernatant clarified by filtration through a 0.2 micrometer filter
- Buffer Solution
- Serum free tissue culture medium containing proprietary protein free supplement
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- ConA activated bovine lymphocytes
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Store at +4oC. DO NOT FREEZE.
Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
serine-type endopeptidase activity
integral to membrane
positive regulation of cell proliferation
negative regulation of extracellular matrix disassembly
apical plasma membrane
T cell costimulation
protein homodimerization activity
endothelial cell migration
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of CD26 antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 106 cells in 100ul
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Secondary Antibodies Available
Useful Reagents Available
Product Specific References
References for CD26 antibody
Lee, S.U. et al. (2002) Molecular characterization of bovine CD26 upregulated by a staphylococcal superantigen.
Immunogenetics. 54 (3): 216-20.
Park, K.T. et al. (2015) Characterization and expression of monoclonal antibody-defined molecules on resting and activated bovine αβ, γδ T and NK cells.
Vet Immunol Immunopathol. 168 (1-2): 118-30.
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