CD26 antibody | CACT114A

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Mouse anti Bovine CD26

Product Type
Monoclonal Antibody
Clone
CACT114A
Isotype
IgG2b
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
MCA6087 F 0.1 mg
Mouse anti Bovine CD26, clone CACT114A, recognizes bovine CD26 also known as DPP4 or dipeptidyl peptidase 4. Bovine CD26 is expressed in various cell types and participates in many biological activities such as the post-translational processing of chemokines (Proost et al. 2001) and neuropeptides (Lambeir et al. 2001), and in the regulation of degradation and inactivation of glucagon (Pospisilik et al. 2001). CD26 also functions as a costimulatory molecule on activated T cells and is highly expressed on CD8+ natural killer cells in calves vaccinated against Mycobacterium avium paratuberculosis (Park et al. 2015).

Product Details

Target Species
Bovine
Product Form
Concentrated tissue culture supernatant - liquid
Preparation
Concentrated tissue culture supernatant clarified by filtration through a 0.2 micrometer filter
Buffer Solution
Serum free tissue culture medium containing proprietary protein free supplement
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
ConA activated bovine lymphocytes
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml

Storage Information

Storage
Store at +4oC. DO NOT FREEZE.
Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
12 months from date of despatch

More Information

UniProt
P81425 Related reagents
Entrez Gene
DPP4 Related reagents
GO Terms
GO:0002020 protease binding
GO:0004252 serine-type endopeptidase activity
GO:0004177 aminopeptidase activity
GO:0008239 dipeptidyl-peptidase activity
GO:0005102 receptor binding
GO:0007155 cell adhesion
GO:0016021 integral to membrane
GO:0005576 extracellular region
GO:0004872 receptor activity
GO:0030139 endocytic vesicle
GO:0006508 proteolysis
GO:0008284 positive regulation of cell proliferation
GO:0009986 cell surface
GO:0010716 negative regulation of extracellular matrix disassembly
GO:0016324 apical plasma membrane
GO:0031258 lamellipodium membrane
GO:0031295 T cell costimulation
GO:0042803 protein homodimerization activity
GO:0043542 endothelial cell migration
GO:0045121 membrane raft
GO:0071438 invadopodium membrane
Regulatory
For research purposes only

Applications of CD26 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Flow Cytometry Neat 1/10
Functional Assays
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Flow Cytometry
Use 10ul of the suggested working dilution to label 106 cells in 100ul

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Goat anti Mouse IgG2b:RPE STAR134PE 0.1 mg F

Useful Reagents Available

Description Product Code Pack Size Applications List Price Quantity
Mouse anti Bovine CD4 MCA6081 0.1 mg F
Mouse anti Bovine CD8a MCA6083 0.1 mg F

Product Specific References

References for CD26 antibody

  1. Lee, S.U. et al. (2002) Molecular characterization of bovine CD26 upregulated by a staphylococcal superantigen.
    Immunogenetics. 54 (3): 216-20.
  2. Park, K.T. et al. (2015) Characterization and expression of monoclonal antibody-defined molecules on resting and activated bovine αβ, γδ T and NK cells.
    Vet Immunol Immunopathol. 168 (1-2): 118-30.