Beta 2 Microglobulin antibody | F21-21

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F ResetMouse anti Chicken Beta 2 Microglobulin
- Product Type
- Monoclonal Antibody
- Clone
- F21-21
- Isotype
- IgG1
- Specificity
- Beta 2 Microglobulin
Mouse anti Chicken β2 microglobulin antibody, clone F21-21 recognises chicken β2 microglobulin, a component of MHC class I molecules and is expressed on nearly all nucleated cells. |
- Target Species
- Chicken
- Species Cross-Reactivity
-
Target Species Cross Reactivity Turkey - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by ion exchange chromatography from tissue culture supernatant
- Buffer Solution
- Borate buffered saline.
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Approx. Protein Concentrations
- IgG concentration 0.5mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
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Flow Cytometry | ![]() |
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Immunohistology - Frozen | ![]() |
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Immunoprecipitation | ![]() |
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Western Blotting | ![]() |
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Goat anti Mouse IgG (H/L):FITC (Multi Species Adsorbed) | STAR117F | F | 0.5 mg | Log in | |||
List Price | Your Price | ||||||
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Description | Goat anti Mouse IgG (H/L):FITC (Multi Species Adsorbed) | ||||||
Goat anti Mouse IgG (H/L):HRP (Multi Species Adsorbed) | STAR117P | C E WB | 0.5 mg | Log in | |||
List Price | Your Price | ||||||
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Description | Goat anti Mouse IgG (H/L):HRP (Multi Species Adsorbed) | ||||||
Rabbit F(ab')2 anti Mouse IgG:RPE | STAR12A | F | 1 ml | Log in | |||
List Price | Your Price | ||||||
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Description | Rabbit F(ab')2 anti Mouse IgG:RPE | ||||||
Rabbit F(ab')2 anti Mouse IgG:FITC | STAR9B | F | 1 mg |
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List Price | Your Price | ||||||
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Description | Rabbit F(ab')2 anti Mouse IgG:FITC |
Source Reference
-
Skjødt, K. et al. (1986) Isolation and characterization of chicken and turkey beta 2-microglobulin.
Mol Immunol. 23 (12): 1301-9.
References for Beta 2 Microglobulin antibody
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Dunon, D. et al. (1990) T cell precursor migration towards beta 2-microglobulin is involved in thymus colonization of chicken embryos.
EMBO J. 9 (10): 3315-22. -
Burgess, S.C. & Davison, T.F. (1999) Counting absolute numbers of specific leukocyte subpopulations in avian whole blood using a single-step flow cytometric technique: comparison of two inbred lines of chickens.
J Immunol Methods. 227 (1-2): 169-76. -
Juul-Madsen, H.R. et al. (2000) Molecular characterization of major and minor MHC class I and II genes in B21-like haplotypes in chickens.
Anim Genet. 31 (4): 252-61. -
Lawson S et al. (2001) Turkey and chicken interferon-gamma, which share high sequence identity, are biologically cross-reactive.
Dev Comp Immunol. 25 (1): 69-82. -
Juul-Madsen, H.R. et al. (2002) Major histocompatibility complex-linked immune response of young chickens vaccinated with an attenuated live infectious bursal disease virus vaccine followed by an infection.
Poult Sci. 81 (5): 649-56. -
Levy, A.M. et al. (2003) Major histocompatibility complex class I is downregulated in Marek's disease virus infected chicken embryo fibroblasts and corrected by chicken interferon.
Comp Immunol Microbiol Infect Dis. 26 (3): 189-98. -
Juul-Madsen, H.R. et al. (2004) Influence of early or late start of first feeding on growth and immune phenotype of broilers.
Br Poult Sci. 45 (2): 210-22. -
Buitenhuis, A.J. et al. (2006) Altered circulating levels of serotonin and immunological changes in laying hens divergently selected for feather pecking behavior.
Poult Sci. 85 (10): 1722-8.
View The Latest Product References
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Wallny, H.J. et al. (2006) Peptide motifs of the single dominantly expressed class I molecule explain the striking MHC-determined response to Rous sarcoma virus in chickens.
Proc Natl Acad Sci U S A. 103 (5): 1434-9. -
Juul-Madsen, H.R. et al. (2006) Immune response to a killed infectious bursal disease virus vaccine in inbred chicken lines with different major histocompatibility complex haplotypes.
Poult Sci. 85 (6): 986-98. -
Walker, B.A. et al. (2011) The dominantly expressed class I molecule of the chicken MHC is explained by coevolution with the polymorphic peptide transporter (TAP) genes.
Proc Natl Acad Sci U S A. 108 (20): 8396-401. -
Butter, C. et al. (2013) The peptide motif of the single dominantly expressed class I molecule of the chicken MHC can explain the response to a molecular defined vaccine of infectious bursal disease virus (IBDV).
Immunogenetics. 65 (8): 609-18.
- RRID
- AB_10842663
- UniProt
- P21611
- Entrez Gene
- B2M
- GO Terms
- GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
- GO:0042612 MHC class I protein complex
- GO:0005576 extracellular region
- GO:0006955 immune response
MCA5774


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