Cholera Toxin antibody | 2/166

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Mouse anti Cholera Toxin Alpha

Product Type
Monoclonal Antibody
Clone
2/166
Isotype
IgM
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
9540-0008 E 0.2 mg
Mouse anti Cholera Toxin alpha antibody, clone 2/166 recognizes the alpha subunit of Cholera toxin.

The cholera holotoxin consists of a pentameric ring of Beta subunits whose central pore is occupied by the Alpha subunit. The Alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The Alpha subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.

Product Details

Target Species
Bacterial
Product Form
Ig fraction - liquid
Preparation
Ig fraction prepared by ammonium sulphate precipitation
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09%Sodium Azide (NaN3)
Immunogen
Vibrio cholerae extract.
Approx. Protein Concentrations
5.0 mg/ml

Storage Information

Storage
Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
P01555 Related reagents
GO Terms
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005576 extracellular region
GO:0006471 protein ADP-ribosylation
GO:0009405 pathogenesis
GO:0031640 killing of cells of other organism
GO:0047286 NAD+-diphthamide ADP-ribosyltransferase activity
Regulatory
For research purposes only

Applications of Cholera Toxin antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Human anti Mouse IgM:FITC HCA040F 0.1 mg F
Goat anti Mouse IgM:Alk. Phos.(Human Adsorbed) STAR138A 1 ml C E P WB
Goat anti Mouse IgM:RPE STAR86PE 0.5 ml F
Goat anti Mouse IgG/A/M:Alk. Phos. STAR87A 1 mg C E WB
Goat anti Mouse IgG/A/M:HRP (Human Adsorbed) STAR87P 1 mg E