Troponin Complex Antibody | 20C6

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  • Mouse anti Human Troponin Complex (Cardiac)
(Rated 0.0 out of 5 based on 0 customer reviews)
  • Product Type
    Monoclonal Antibody
  • Clone
    20C6
  • Isotype
    IgG2b
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    MCA2774Edatasheet pdfdatasheet pdf0.2 mg
    MCA2774
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
    -
    • Mouse anti Human Troponin Complex (Cardiac) antibody, clone 20C6 recognizes human troponin, a complex of three proteins integral to muscle contraction. The three-unit troponin complex (Troponin I, T and C), bound to tropomyosin, is located on the actin filament of skeletal and cardiac muscle. Troponin T binds to tropomyosin to form the troponin-tropomyosin complex. Troponin C binds calcium ions to produce a conformational change in Troponin I. Troponin I binds to the actin in thin myofilaments to hold the troponin-tropomyosin complex in place. When calcium binds to troponin, a conformation change is forced in troponin and tropomyosin, moving both proteins away from the myosin binding sites on the actin filaments. Thus, myosin can bind to actin and muscle contraction occurs.

      Mouse anti Human Troponin Complex (Cardiac) antibody, clone 20C6 recognizes the native troponin complex. It does not cross-react with any of the individual components Troponin I, T or C.
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      ELISA

    • Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional Troponin Complex Antibody Formats

    Formats Clone Applications Sizes available
    Troponin Complex Antibody : Purified 20C6 E 0.2 mg
    • Copyright © 2016 Bio-Rad Antibodies (formerly AbD Serotec)

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      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls

              References

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