Thyroid Hormone Receptor Beta Antibody | 2386

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Thyroid Hormone Receptor Beta Antibody | 2386 gallery image 1

Western blot of hippocampal lysate showing specific immunolabeling of the ~55 kDa TR-β protein

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  • Thyroid Hormone Receptor Beta Antibody | 2386 thumbnail image 1
  • Mouse anti Human Thyroid Hormone Receptor Beta
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  • Product Type
    Monoclonal Antibody
  • Clone
    2386
  • Isotype
    IgG1
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    MCA4748WBdatasheet pdfdatasheet pdf0.1 ml
    MCA4748
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
    -
    • Mouse anti Human Thyroid Hormone Receptor beta antibody, clone 2386 recognizes thyroid hormone receptor beta, one of several receptors for thyroid hormone. The thyroid hormone receptors, in association with the thyroid hormones, are responsible for the regulation of metabolism and heart rate and play a critical role in the development of the central nervous system. Thyroid hormone receptor beta has high affinity for triiodothyronine (T3).
    • Intended Use
    • Target Species
      Human
    • Product Form
      Purified IgG - liquid
    • Reconstitution
    • Preparation
      Purified IgG prepared by affinity chromatography on Protein G from mouse ascites.
    • Preservative Stabilisers
      0.09% Sodium Azide (NaN3)
      0.01% Bovine Serum Albumin
      50% Glycerol
    • Immunogen
      Peptide corresponding to amino acid residues from the N-terminal region of human thyroid hormone receptor, Beta isotype.
    • Purity
    • Approx. Protein Concentrations
    • Reagents In The Kit
    • Preparing The Antibody
    • Test Principle
    • Buffer Solution
      10mM HEPES, pH7.5, 150mM NaCl
    • Storage
      Store at +4oC or at -20oC if preferred.
      Storage in frost-free freezers is not recommended.
      This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
    • Shelf Life
      18 months from date of despatch.
    • GO Terms
      zinc ion binding
      nucleoplasm
      regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
      sequence-specific DNA binding transcription factor activity
      thyroid hormone receptor activity
      steroid hormone receptor activity
      sequence-specific DNA binding
      enzyme binding
      transcription corepressor activity
    • UniProt
    • Entrez Gene
    • Acknowledgements
    • Regulatory
      For research purposes only
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Western Blotting1/1000

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
      MCA4748 detects a band of approximately 58kDa in hippocampal lysate.
    • Instructions For Use

    Additional Thyroid Hormone Receptor Beta Antibody Formats

    Formats Clone Applications Sizes available
    Thyroid Hormone Receptor Beta Antibody : Purified 2386 WB 0.1 ml
    • Copyright © 2016 Bio-Rad

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      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls

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