Browsing Modes for Business Users

TGN46 antibody

Product Code Applications Pack Size List Price Your Price Qty
AHP1586
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
IF * WB 0.1 ml loader
List Price Your Price
loader

Rabbit anti Human TGN46 antibody recognizes Trans-Golgi network integral membrane protein 2, also known as TGN46, TGN38 homolog or Trans-Golgi network protein TGN51. TGN46 is a 480 amino acid ~110kDa single pass type I transmembrane glycoprotein associated with the trans golgi network membrane. TGN46 has been reported as being the best available marker for human trans-Golgi network.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Primate
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Serum - liquid
Antiserum Preparation
Antisera to human TGN46 were raised by repeated immunisation of rabbits with highly purified recombinant human TGN46.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
<0.1% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin
50% Glycerol
Immunogen
Recombinant human TGN46.
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunofluorescence 1 1/50 1/100
Western Blotting 1/500 1/000
  1. 1Fixation of tissues with 3% paraformaldehyde or methanol is recommended prior to using this antibody on immunofluorescence.
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.

Description Product Code Applications Pack Size List Price Your Price Quantity
Goat anti Rabbit IgG (Fc):Biotin STAR121B E WB 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (Fc):Biotin
Goat anti Rabbit IgG (Fc):FITC STAR121F F 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (Fc):FITC
Goat anti Rabbit IgG (Fc):HRP STAR121P E WB 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (Fc):HRP
Goat anti Rabbit IgG (H/L):HRP STAR124P C E WB 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (H/L):HRP
Sheep anti Rabbit IgG:RPE STAR35A F 1 ml loader
List Price Your Price
loader
Description Sheep anti Rabbit IgG:RPE

Description Product Code Applications Pack Size List Price Your Price Quantity
TidyBlot Western Blot Detection Reagent:HRP STAR209P WB * 0.5 ml
List Price Your Price
Description TidyBlot Western Blot Detection Reagent:HRP

References for TGN46 antibody

  1. Ponnambalam, S. et al. (1996) Primate homologues of rat TGN38: primary structure, expression and functional implications.
    J Cell Sci. 109 ( Pt 3): 675-85.
  2. Prescott, A.R. et al. (1997) Distinct compartmentalization of TGN46 and beta 1,4-galactosyltransferase in HeLa cells.
    Eur J Cell Biol. 72 (3): 238-46.
  3. Sandri, C. et al. (2012) The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling.
    Cell Res. 22 (10): 1479-501.
  4. Aydin, I. et al. (2014) Large scale RNAi reveals the requirement of nuclear envelope breakdown for nuclear import of human papillomaviruses.
    PLoS Pathog. 10 (5): e1004162.
  5. Cerqueira, C. et al. (2015) Kallikrein-8 Proteolytically Processes Human Papillomaviruses in the Extracellular Space To Facilitate Entry into Host Cells.
    J Virol. 89 (14): 7038-52.
  6. Striebinger, H. et al. (2016) Subcellular Trafficking and Functional Relationship of the HSV-1 Glycoproteins N and M.
    Viruses. 8 (3): pii: E83.
  7. Groux-Degroote, S. et al. (2018) The extended cytoplasmic tail of the human B4GALNT2 is critical for its Golgi targeting and post-Golgi sorting.
    FEBS J. 285 (18): 3442-63.
  8. Song, O.R. et al. (2018) ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton.
    EMBO Rep. 19 (1): 29-42.
  9. View The Latest Product References

Synonyms
TGOLN2
RRID
AB_2303333
UniProt
O43493
Entrez Gene
TGOLN2

AHP1586

166922 170114

If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.

View more products with TGN46 specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products
Please note