Tenascin
Native Human Tenascin
- Product Type
- Purified Protein
- Specificity
- Tenascin
Purified human Tenascin is a preparation of human tenascin prepared from tissue culture supernatant of the glioblastoma U-251 MG, formally distributed as U-373 MG, an astrocytoid adherent cell line, an over producer of human tenascin. Tenascin is a secreted peptide found in the extracellular matrix that plays an active role in the development of the CNS and mesenchymal derived organs. It is also present in adult tumour vasculature and has functions in cell adhesion. |
- Target Species
- Human
- Product Form
- Purified protein from tissue culture supernatant - liquid
- Preparation
- Purified from tissue culture supernatant of the overproducing cell line, U251, using precipitation, concentration and dialysis.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present.
- Purity
- >97% by SDS PAGE
- Approx. Protein Concentrations
- Total protein concentration 0.1 mg/ml
- Protein Molecular Weight
- Migrates at 280-300 kDa in SDS PAGE analysis
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA |
- ELISA
- This product represents a suitable standard for use with 8640-0208 in a direct ELISA system.
References for Tenascin
-
Maqbool, A. et al. (2016) Tenascin C upregulates interleukin-6 expression in human cardiac myofibroblasts via toll-like receptor 4.
World J Cardiol. 8 (5): 340-50.
- UniProt
- P24821
- Entrez Gene
- TNC
- GO Terms
- GO:0005102 receptor binding
- GO:0007155 cell adhesion
- GO:0007165 signal transduction
- GO:0005615 extracellular space
- GO:0009611 response to wounding
- GO:0045545 syndecan binding
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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