tau Antibody

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tau Antibody gallery image 1

Immunohistochemical detection of tau in a brain section from a patient with Alzheimer's disease showing localization to neurofuinrillary tangles using Goat anti Human tau antibody (AHP738)

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tau Antibody gallery image 2

Western blot analysis of human tau protein expression in human brain lystate using Goat anti Human tau antibody (AHP738) at a dilution of 1/1000

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tau Antibody gallery image 3

Detection of human tau proteins in paired helical filaments in a brain section from a patient with Alzheimer's disease using Goat anti tau antibody (AHP738) at a dilution of 1/200 followed by a colloidal gold conjugated anti goat IgG

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  • Goat anti Human tau (aa1-16)
(Rated 0.0 out of 5 based on 0 customer reviews)
  • Product Type
    Polyclonal Antibody
  • Isotype
    Polyclonal IgG
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    AHP738P *, WBdatasheet pdfdatasheet pdf0.1 ml
    AHP738
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
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    • Goat anti Human tau antibody recognizes the N-terminal region of human Microtubule-associated protein tau, also known as tau, Neurofibrillary tangle protein or Paired helical filament-tau. Tau is a a ~50-70 kDa heterogeneous group of proteins that are involved in microtubule assembly. In healthy brain tissue tau is localized to the axons of neurons.

      Tau has been associated with some neurological disease states including Alzheimer's disease where it localizes to neurofibrillary tangles (Goedert et al. 1989).

      Several isoforms of human tau can be generated by alternative splicing, Goat anti Human tau antibody is expected to recognize all isoforms with the possible exception of isoform-3 which demonstrates multiple residue changes within the region of the immunizing peptide.
    • Intended Use
    • Target Species
      Human
    • Product Form
      Serum - liquid
    • Reconstitution
    • Preparation
    • Antiserum Preparation
      Antisera to human Tau were raised by repeated immunisations of goats with highly purified antigen.
    • Preservative Stabilisers
      0.1%Sodium Azide
    • Immunogen
      Synthetic peptide MAEPRQEFEVMEDHAG corresponding to amino acids 1-16 of human Tau.
    • Purity
    • Approx. Protein Concentrations
    • Reagents In The Kit
    • Preparing The Antibody
    • Test Principle
    • Buffer Solution
    • Storage
      Store at +4oC or at -20oC if preferred.

      This product should be stored undiluted.

      Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
    • Shelf Life
      18 months from date of despatch.
    • UniProt
    • Entrez Gene
    • Acknowledgements
    • Regulatory
      For research purposes only
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Western Blotting1/1000
      Immunohistology - Paraffin(1)1/501/100
      (1)
      This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.

    • Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional tau Antibody Formats

    Formats Applications Sizes available
    tau Antibody : Serum P *, WB 0.1 ml
    • Copyright © 2016 Bio-Rad

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      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls

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