SMAD7 Antibody | 1G10

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SMAD7 Antibody | 1G10 gallery image 1

Staining of paraffin-embedded human placenta with Mouse anti Human SMAD7 (MCA5343Z)

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  • SMAD7 Antibody | 1G10 thumbnail image 1
  • Mouse anti Human SMAD7:Preservative Free
(Rated 0.0 out of 5 based on 0 customer reviews)
  • Product Type
    Monoclonal Antibody
  • Clone
    1G10
  • Isotype
    IgG2a
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    MCA5343ZP, WBdatasheet pdfdatasheet pdf0.1 mg
    MCA5343Z
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
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    References
    Reviews
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    • Mouse anti Human SMAD7, clone 1G10 recognizes human Mothers against decapentaplegic homolog 7, also known as SMAD7, Mothers against decapentaplegic homolog 8 or SMAD family member 7. SMAD7 is a 426 amino acid ~45-50 kDa antagonist of signaling by TGF-beta type 1 receptor superfamily members through binding to their receptors (Lebrun et al. 1999).

      Three isoforms of SMAD7 produced by alternative splicing have been described. Mouse anti Human SMAD7, clone 1G10 is expected to recognize all described isoforms of SMAD7 (UniProt : O15105).

      Mutations in the SMAD7 gene have been implicated in changes to the susceptibility to Colorectal cancer 3 (CRCS3).
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Immunohistology - Paraffin0.110 ug/ml
      Western Blotting0.110 ug/ml

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional SMAD7 Antibody Formats

    Formats Clone Applications Sizes available
    SMAD7 Antibody : Preservative Free 1G10 P, WB 0.1 mg
    • Copyright © 2016 Bio-Rad

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      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls

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