SERPINI1 Antibody | 1D10

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SERPINI1 Antibody | 1D10 gallery image 1

Staining of paraffin embedded human cerebral cortex with Mouse anti Human SERPINI1:Azide Free (MCA3339Z)

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SERPINI1 Antibody | 1D10 gallery image 2

Western blot analysis of SERPINI1 expression in HeLa using Mouse anti Human SERPINI1:Azide Free (MCA3339Z)

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  • SERPINI1 Antibody | 1D10 thumbnail image 1
  • SERPINI1 Antibody | 1D10 thumbnail image 2
  • Mouse anti Human SERPINI1:Preservative Free
(Rated 0.0 out of 5 based on 0 customer reviews)
  • Product Type
    Monoclonal Antibody
  • Clone
    1D10
  • Isotype
    IgG1
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    MCA3339ZP *, WBdatasheet pdfdatasheet pdf0.1 mg
    MCA3339Z
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
    -
    • Mouse anti Human SERPINI1 antibody, clone 1D10 recognizes human Neuroserpin, also known as SERPINI1, Peptidase inhibitor 12 or Serpin I1. SERPINI1 is a 394 amino acid ~48 kDa serine protease inhibitor involved in inhibition of plasminogen activators and plasmin but not thrombin. Mutations in the SERPINI1 gene can lead to development of Encephalopathy, familial, with neuroserpin inclusion bodies (FENIB), a neurodegenerative disease characterized by dementia (Davis et al. 1999)
    • Intended Use
    • Target Species
      Human
    • Product Form
      Purified IgG - liquid
    • Reconstitution
    • Preparation
      Purified IgG prepared by affinity chromatography on Protein A
    • Preservative Stabilisers
      None present
    • Immunogen
      Recombinant protein corresponding to aa 17-411 of human SERPINI1
    • Purity
    • Approx. Protein Concentrations
      Ig concentration 0.5 mg/ml
    • Reagents In The Kit
    • Preparing The Antibody
    • Test Principle
    • Buffer Solution
      Phosphate buffered saline
    • Fusion Partners
      Spleen cells from Balb/c mice were fused with cells from the Sp2/0 myeloma cell line.
    • Storage
      Store at -20oC only.
      Storage in frost-free freezers is not recommended.
      This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
    • Shelf Life
      18 months from date of despatch.
    • GO Terms
      serine-type endopeptidase inhibitor activity
      extracellular region
      peripheral nervous system development
      central nervous system development
    • UniProt
    • Entrez Gene
    • Acknowledgements
    • Regulatory
      For research purposes only
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Western Blotting0.110 ug/ml
      Immunohistology - Paraffin(1)0.110 ug/ml
      (1)
      This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional SERPINI1 Antibody Formats

    Formats Clone Applications Sizes available
    SERPINI1 Antibody : Preservative Free 1D10 P *, WB 0.1 mg
    • Copyright © 2016 Bio-Rad

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      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls

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