Synthetic Human prolactin receptoris a peptide corresponding to the N-terminal region of the human prolactin receptor, a 598 amino acid single pass type I transmembrane glycoprotein receptor for the anterior pituitary hormone prolactin. Mutation of the prolactin receptor gene can lead to Multiple fibroadenomas of the breast (MFAB) and Hyperprolactinemia (HPRL), characterized by elevated circulating prolactin levels, not associated with puerperium or gestation (Newey et al. 2013).
Semi purified synthetic peptide - lyophilised
With sterile DI water to >= 2.0 mg/ml.
Solid phase synthesis
Q-L-P-P-G-K-P-E-I-F-K-C-R-S This N terminal human sequence is in an area of the molecule where rat and mouse (1-3) receptors exhibit a high degree of homology.
Approx. Protein Concentrations
Reagents In The Kit
Preparing The Antibody
Prior to reconstitution store at +4oC. After reconstitution store at -20oC. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.