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  • Recombinant Human NT-4
(Rated 0.0 out of 5 based on 0 customer reviews)
  • Product Type
    Recombinant Protein
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    PHP167FNdatasheet pdfdatasheet pdf10 µg
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    • Neurotrophin-4 (NT-4) is a 28 kDa neurotrophic factor and member of the cysteine knot family of growth factors, which signals via LNGFR and trkB receptors and is involved in the control, survival and differentiation of peripheral sensory sympathetic neurons. Bronchial eosinophils, activated by NT-4, may be involved in the regulation of eosinophilic inflammation in allergic asthma. NT-4 influences airway smooth muscle intracellular Ca2+ concentration which may play a role in airway disease.

      Expression of NT-4 occurs in embryonic and adult tissues. The highest levels are found in the prostate with lower levels in thymus, placenta, and skeletal muscle.
    • Intended Use
    • Target Species
    • Product Form
      Purified recombinant protein - lyophilised
    • Reconstitution
      Reconstitute with 100ul distilled water
      Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
    • Preparation
      Purified recombinant NT-4, expressed in E. coli
    • Preservative Stabilisers
      None present
    • Activity
      Determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50ng/ml.
    • Purity
      >98% by SDS PAGE and HPLC analysis
    • Approx. Protein Concentrations
    • Molecular Weight
    • Reagents In The Kit
    • Preparing The Antibody
    • Endotoxin Level
    • Test Principle
    • Buffer Solution
    • Storage
      Prior to reconstitution store at +4oC.
      After reconstitution store at -20oC only.
      Avoid repeated freezing and thawing as this may denature the protein. This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
    • Shelf Life
      3 months from date of reconstitution.
    • GO Terms
      epidermis development
      extracellular region
      adult locomotory behavior
      sensory organ boundary specification
      growth factor activity
      ganglion mother cell fate determination
      endoplasmic reticulum lumen
      long-term memory
    • UniProt
    • Entrez Gene
    • Acknowledgements
    • Regulatory
      For research purposes only
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Functional Assays

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional NT-4 Formats

    Formats Applications Sizes available
    NT-4 : Rec. Protein FN 10 µg
    • Copyright © 2016 Bio-Rad

    Recommended Secondary Antibody

      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls


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