NFkB p105 Antibody

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NFkB p105 Antibody gallery image 1

Western blot analysis of 3T3 cell lysate (lane 1) and Jurkat cell lysate (lane 2 & 3) probed with Rabbit anti NFkB p105 antibody

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  • Rabbit anti NFkB p105
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  • Product Type
    Polyclonal Antibody
  • Isotype
    Polyclonal IgG
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    AHP2330WBdatasheet pdfdatasheet pdf50 µg
    AHP2330
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
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    References
    Reviews
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    • Rabbit anti NFkB p105 antibody recognizes Nuclear factor NF-kappa-B p105 subunit also known as DNA-binding factor KBF1 and Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. NF-kappa-B p105 is a large precursor protein that is cleaved at its C-terminus (which mainly contains ankyrin repeats) by the ubiquitin/proteasome pathway into the NF-kappa-B p50 subunit. The p50 subunit is also known as NF-κB1 and interacts with members of the Rel protein family to form transcription factors. In the absence of stimulation an I-kappa-B inhibitory protein mediated sequestration mechanism ensures that the transcription factors remain in the cytoplasm. Upon stimulation, I-kappa-B proteins become phosphorylated, which results in their ubiquitylation and subsequent degradation by the 26S proteasome.The NF-kappa-B pathway plays a critical in mediating immune responses after infection and has been implicated in a variety of diseases ranging from autoimmune disorders to cancer.
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Western Blotting0.54.0 ug/ml

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
      Rabbit anti NFkB (p105) antibody recognizes a band of approximately 105 kDa in 3T3 cell lysate and Jurkat cell lysate
    • Instructions For Use

    Additional NFkB p105 Antibody Formats

    Formats Applications Sizes available
    NFkB p105 Antibody : Purified WB 50 µg
    • Copyright © 2016 Bio-Rad Antibodies (formerly AbD Serotec)

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      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls

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