Neuron Specific Enolase Antibody | 131.1C10

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Neuron Specific Enolase Antibody | 131.1C10 gallery image 1

Neuron specific enolase detected with Mouse anti Human neuron specific enolase (MCA5867S) followed by Goat anti Mouse IgM:HRP (STAR86P)

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  • Product Type
    Monoclonal Antibody
  • Clone
    131.1C10
  • Isotype
    IgM
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    MCA5867SEdatasheet pdfdatasheet pdf2 ml
    MCA5867S
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
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    • Mouse anti Human neuron specific enolase (131.1C10) is a monoclonal antibody recognising neuron specific enolase, also known as gamma enolase or enolase 2. Neuron specific enolase is a glycolytic enzyme catalizing the conversion of 2-phosphoglycerate to phosphoenolpyruvate. Neuron specific enolase is principally localized to the neuronal cytoplasm (Berger et al. 2002).

      Neuron specific enolase is a ~78kDa gamma homodimer, the most acidic isoenzyme of the enolase family. Levels of neuron specific enolase in the cerebrospinal fluid are often elevated in conditions resulting in rapid neuronal destruction such as Creutzfeldt-Jacob Disease (Wakayama et al. 1987).
    • Intended Use
    • Target Species
      Human
    • Product Form
      Tissue Culture Supernatant - liquid
    • Reconstitution
    • Preparation
    • Preservative Stabilisers
      0.09% Sodium Azide (NaN3)
    • Purity
    • Approx. Protein Concentrations
    • Reagents In The Kit
    • Preparing The Antibody
    • Test Principle
    • Buffer Solution
    • Storage
      Store at +4oC or at -20oC if preferred.
      Storage in frost-free freezers is not recommended.
      This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
    • Shelf Life
      18 months from date of despatch.
    • GO Terms
      glycolysis
      magnesium ion binding
      plasma membrane
      gluconeogenesis
      phosphopyruvate hydratase activity
      phosphopyruvate hydratase complex
    • UniProt
    • Entrez Gene
    • Acknowledgements
    • Regulatory
      For research purposes only
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      ELISANeat1/20

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional Neuron Specific Enolase Antibody Formats

    Formats Clone Applications Sizes available
    Neuron Specific Enolase Antibody : S/N 131.1C10 E 2 ml
    • Copyright © 2016 Bio-Rad

    Recommended Secondary Antibody

      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls

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