MRE11 Antibody

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Detection of human Mre11 in whole cell lysates of HeLa cells by Western blotting using Rabbit anti Human Mre11 (AHP843)

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  • Rabbit anti Human MRE11
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  • Product Type
    Polyclonal Antibody
  • Isotype
    Polyclonal IgG
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    AHP843WBdatasheet pdfdatasheet pdf0.1 mg
    AHP843
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
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    References
    Reviews
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    • Rabbit anti human MRE11 antibody recognizes human meiotic recombination 11 (MRE11), also known as Double-strand break repair protein MRE11A or ATLD. MRE11 is a 708 amino acid nuclear protein component of the MRN complex (van den Bosch et al. 2003) which is involved in homologous recombination, telomere length maintenance through interaction with LSD1 (Porro et al. 2014) and DNA double-strand break repair (Shibata et al. 2014). MRE11 has 3' to 5' exonuclease activity and endonuclease activity (Paull et al. 1998).

      Mutations in this gene are associated with Ataxia telangiectasia-like disorder, which is characterized by hypersensitivity to ionizing radiation and defective checkpoint responses (Petrini et al. 2000).
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Immunoprecipitation
      Western Blotting1/10001/5000

    • Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional MRE11 Antibody Formats

    Formats Applications Sizes available
    MRE11 Antibody : Purified WB 0.1 mg
    • Copyright © 2016 Bio-Rad

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      Recommended Negative Isotype Control

        Useful Reagents

          DescriptionProduct CodePack SizeApplicationsList PriceQuantity
          TidyBlot Western Blot Detection Reagent:HRPSTAR209P0.5 mlWB*
          STAR209P

          Recommended Positive Controls

            Histology Controls

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