MEK 2 Antibody (PrecisionAbTM Antibody)

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MEK 2 Antibody (PrecisionAb<sup>TM</sup> Antibody) gallery image 1

Western blot analysis of whole cell lysates probed with MEK 2 antibody followed by detection with HRP conjugated Goat anti Rabbit IgG antibody (1/10,000, STAR208P) and visualized on the ChemiDoc™ MP with 14 second exposure. Arrow points to MEK 2 (molecular weight 49 kDa)

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  • MEK 2 Antibody (PrecisionAb<sup>TM</sup> Antibody) thumbnail image 1
  • Rabbit anti MEK 2
  • MEK 2 Antibody with Control Lysate
(Rated 0.0 out of 5 based on 0 customer reviews)
    Rabbit anti-human MEK2 antibody recognizes dual specificity mitogen-activated protein kinase kinase 2, also known as ERK activator kinase 2, MAPK/ERK kinase 2 or mitogen-activated protein kinase kinase 2, p45. This antibody has been extensively validated for western blotting using whole cell lysates.
    • Product Type
      PrecisionAb™ Polyclonal
    • Isotype
      Polyclonal IgG
    • Format
      Purified
      Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
      VPA00587WBdatasheet pdfdatasheet pdf100 µl
      VPA00587
      VPA00587KTWBdatasheet pdfdatasheet pdf datasheet pdf2 Westerns
      VPA00587KT
      Summary
      Secondary Antibodies
      Negative Isotype Controls
      Useful Reagents
      Positive Controls
      Histology Controls
      References
      Reviews
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      • Rabbit anti Human MEK 2 antibody recognizes MEK 2 also known as dual specificity mitogen-activated protein kinase kinase 2, also known as ERK activator kinase 2, MAP kinase kinase 2, MAPK/ERK kinase 2, MAPKK2 or p45.

        The protein encoded by MAP2K2 gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in MAP2K2 gene cause Cardiofaciocutaneous syndrome 4 (CFC4), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome (Schulz et al. 2008). The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for MAP2K2 (provided by RefSeq, Jul 2008).

        Rabbit anti Human MEK 2 antibody detects a band of 49 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
      • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
      • Application NameYesNoMin DilutionMax Dilution
        Western Blotting1/1000
      • Application NameYesNoMin DilutionMax Dilution
        Western Blotting1/1000

      • PrecisionAb antibodies have been extensively validated for the western blot application. The antibody has been validated at the suggested dilution. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.
      • Copyright © 2017 Bio-Rad Antibodies (formerly AbD Serotec)

      Recommended Secondary Antibody

        DescriptionProduct CodePack SizeApplicationsList PriceQuantity
        Goat anti Rabbit IgG (H/L):HRPSTAR208P2 mlWB
        STAR208P
        DescriptionProduct CodePack SizeApplicationsList PriceQuantity
        Goat anti Rabbit IgG (H/L):HRPSTAR208P2 mlWB
        STAR208P

        Recommended Negative Isotype Control

          Useful Reagents

            Recommended Positive Controls

              Histology Controls

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