Lyn Antibody | 2974

Lyn Antibody | 2974 gallery image 1

Western blot of total cell lysates using HCA026. Cell lines used, from left to right, are as below:- 1: U2OS 2: SiHa 3: A375 4: H4 5: HCT116 6: H460 7: Du-145 8: MCF7

  • Lyn Antibody | 2974 thumbnail image 1
  • Human anti Human Lyn
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  • Product Type
    Monoclonal Antibody
  • Clone
  • Isotype
    HuCAL Fab bivalent
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    HCA026E, WBdatasheet pdfdatasheet pdf0.1 mg
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    • Human anti Human Lyn antibody, clone 2974 recognizes the human Tyrosine-protein kinase Lyn, a 512 amino acid ~56kDa member of the Src family of kinases containing signle protein kinase, SH2 and SH3 domains. Lyn is also known as Lck/Yes-related novel protein tyrosine kinase, p53Lyn or p56Lyn.

      Lyn is predominantly expressed in haematopoietic cells, and is involved in signalling from cell surface receptors such as CD40 and sIg. Lyn plays multiple roles in processes such a proliferation, B-cell regulation and autoimmunity (Ingley 2012). Lyn expression has also been reported on human malignant lymphomas (Choi et al. 1993).
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Western Blotting1/1001/500

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
      Recommended protocols and further information about HuCAL recombinant antibody technology can be found in the HuCAL Antibodies Technical Manual
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional Lyn Antibody Formats

    Formats Clone Applications Sizes available
    Lyn Antibody : Purified 2974 E, WB 0.1 mg
    • Copyright © 2017 Bio-Rad Antibodies (formerly AbD Serotec)

    Recommended Secondary Antibody

      DescriptionProduct CodePack SizeApplicationsList PriceQuantity
      Mouse anti c-Myc:HRPMCA2200P0.1 mgC, E, P, WB*
      Mouse anti Penta Histidine Tag:HRPMCA5995P125 µlE, WB

      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls

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