LRP6 Antibody

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Staining of formalin fixed, paraffin embedded human liver with Rabbit anti Human LRP6 (AHP1559)

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  • Rabbit anti Human LRP6
(Rated 0.0 out of 5 based on 0 customer reviews)
  • Product Type
    Polyclonal Antibody
  • Isotype
    Polyclonal IgG
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    AHP1559E, P *datasheet pdfdatasheet pdf50 µg
    AHP1559
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
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    • Rabbit anti Human LRP6 antibody recognizes human Low density lipoprotein receptor related-protein 6 (LRP6), a 180.4 kDa single pass type 1 membrane protein belonging to the LDLR family.

      LRP6 is an essential component of the Wnt/beta catenin signalling pathway where it is believed to act as a co-receptor with Frizzled for Wnt. It is a specific high affinity receptor for DKK1 and DKK2.

      LRP6 is implicated in a wide range of normal and disease processes connected with lipid metabolism. It is co-expressed with LDR5 during embryogenesis and in adult tissues. Defects in LRP6 cause autosomal dominant coronary artery disease type 2.
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      ELISANeat1/1000
      Immunohistology - Paraffin(1)10ug/ml
      (1)
      This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
      Human liver
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional LRP6 Antibody Formats

    Formats Applications Sizes available
    LRP6 Antibody : Purified E, P * 50 µg
    • Copyright © 2016 Bio-Rad Antibodies (formerly AbD Serotec)

    Recommended Secondary Antibody

      DescriptionProduct CodePack SizeApplicationsList PriceQuantity
      Sheep anti Rabbit IgG:HRP (Multi Adsorbed)STAR541 mgC, E, WB
      STAR54

      Recommended Negative Isotype Control

        Useful Reagents

          DescriptionProduct CodePack SizeApplicationsList PriceQuantity
          Antigen Retrieval Buffer, pH8.0BUF025C50 mlP
          BUF025C
          Histar Detection SystemSTAR3000A50 TestsC, P
          STAR3000A
          Antigen Retrieval Buffer, pH8.0BUF025A500 mlP
          BUF025A

          Recommended Positive Controls

            Histology Controls

              Human liver

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