Rabbit anti LGP2 (N-Terminal) antibody recognizes human Probable ATP-dependent helicase LGP2 (LGP2), also known as DHX58, a 768aa cytoplasmic protein belonging to the Helicase family.
LGP2 is a negative regulator of host innate immune defense against viruses. The repressor domain of LGP2 interacts with RIG-I and negatively regulates RIG-I mediated signaling. LGP2 binds to dsRNA produced during viral replication, in particuliar HCV RNA.
N.B. Antibody reactivity and working conditions may vary between species.
Purified IgG - liquid
Antisera to human LGP2 (N-Terminal) were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography.
0.02% Sodium Azide (NaN3)
Peptide corresponding to a 14 amino acid sequence from near the amino terminus of human LGP2.
Approx. Protein Concentrations
IgG concentration 1.0mg/ml
Reagents In The Kit
Preparing The Antibody
Phosphate buffered saline
Store at +4oC or at -20oC if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Histology Positive Control Tissue
AHP1777 detects a band of approximately 41 kDa in MDA-MB-361 cell lysate.